SCHEMBL871668

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3023234	1.00	PDE4B (0.52)	PDE4BGRIN1GRIN2BCYP3A4CYP2C9
	SCHEMBL871876	0.92	PDE4B (0.48)	PDE4BKCNH2ABL1HPGDS
	SCHEMBL871877	0.92	PDE4B (0.48)	PDE4BKCNH2ABL1HPGDS
	SCHEMBL870433	0.91	PDE4B (0.49)	PDE4BCYP3A4CYP2C9CYP2C19KCNH2
	SCHEMBL870434	0.91	PDE4B (0.49)	PDE4BCYP3A4CYP2C9CYP2C19KCNH2
	SCHEMBL871984	0.91	PDE4B (0.47)	PDE4BKCNH2HPGDS
	SCHEMBL872121	0.91	PDE4B (0.47)	PDE4BKCNH2HPGDS
	SCHEMBL871142	0.91	PDE4B (0.64)	PDE4BCYP3A4CYP2C9CYP2C19KCNH2
	SCHEMBL871143	0.91	PDE4B (0.64)	PDE4BCYP3A4CYP2C9CYP2C19KCNH2
	SCHEMBL3016921	0.90	PDE4B (0.46)	PDE4BKCNH2ABL1HPGDS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.