Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 14/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9252332 | 0.79 | F2 (0.47) | F2F10PLGPLATPRSS1 | |
| Acetic Acid SCHEMBL8947565 | 0.73 | F2 (0.53) | F2 | |
| Acetic Acid SCHEMBL8721804 | 0.71 | F2 (0.43) | F2F10PLGPLATPRSS1 | |
| Acetic Acid SCHEMBL8719567 | 0.71 | F2 (0.43) | F2F10PLGPLATPRSS1 | |
| SCHEMBL7306964 | 0.70 | F2 (0.60) | F2NPY5R | |
| Acetic Acid SCHEMBL8947746 | 0.70 | F2 (0.58) | F2NPY5R | |
| SCHEMBL7300995 | 0.70 | F2 (0.43) | F2 | |
| SCHEMBL9003182 | 0.70 | F2 (0.60) | F2 | |
| Acetic Acid SCHEMBL8720013 | 0.69 | F2 (0.43) | F2F10PLGPLATPRSS1 | |
| Acetic Acid SCHEMBL8719928 | 0.69 | F2 (0.43) | F2F10PLGPLATPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763604-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | disclosed |
| US-5677448-A | CHEMICAL INTERMEDIATES FOR MAKING ANTAGONIST OF THROMBIN, TREATING THROMBOSIS, STROKE, INFLAMMATION, ARTERIOSCLEROSIS, CARDIOVASCULAR DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1997-10-14 | — | — | US | disclosed |