Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30022180 | 0.76 | — | — | |
| SCHEMBL250764 | 0.76 | — | — | |
| Ammonia Solution, Strong SCHEMBL28054333 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL3580031 | 0.73 | HSP90AA1 (0.39) | HSP90AA1KCNH3P2RX7CYP2D6NAMPT | |
| SCHEMBL805513 | 0.73 | — | — | |
| SCHEMBL24618427 | 0.72 | HSP90AA1 (0.35) | HSP90AA1KCNH3P2RX7CYP2D6NAMPT | |
| SCHEMBL19597662 | 0.71 | — | — | |
| SCHEMBL650452 | 0.71 | — | — | |
| SCHEMBL1821163 | 0.71 | — | — | |
| SCHEMBL11364572 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853621-A1 | NOVEL SUBSTITUTED AZACYCLIC OR AZABICYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-07-22 | — | — | EP | disclosed |
| WO-1997011072-A1 | NOVEL SUBSTITUTED AZACYCLIC OR AZABICYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1997-03-27 | — | — | WO | disclosed |