SCHEMBL8717826

SCHEMBL8717826

COCCCCCCNC(=O)OC1CCN(Cc2ccccc2)CC1

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
BCHE P06276 2/20 0.60
MCHR1 Q99705 2/20 0.51
POLB P06746 1/20 0.49
SLC6A12 P48065 2/20 0.49
TMEM97 Q5BJF2 1/20 0.49
SIGMAR1 Q99720 1/20 0.49
LMNA P02545 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
KCNA3 P22001 1/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
ACHE P22303 1/20 0.47
CHRM4 P08173 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8480272 0.88 BCHE (0.63) BCHEMCHR1SLC6A12TMEM97SIGMAR1
SCHEMBL8480700 0.88 BCHE (0.55) BCHELMNASMN1; SMN2ACHE
SCHEMBL4464631 0.86 BCHE (0.65) BCHELMNASMN1; SMN2
SCHEMBL11312955 0.81 BCHE (0.70) BCHESIGMAR1ACHE
SCHEMBL8710511 0.79 BCHE (0.47) BCHELMNASMN1; SMN2ACHE
SCHEMBL5901103 0.79 BCHE (0.74) BCHESIGMAR1SMN1; SMN2ACHE
SCHEMBL27756963 0.76 BCHE (0.69) BCHESIGMAR1LMNAMEN1KMT2A
SCHEMBL30290547 0.75 NPFFR1 (0.52) BCHESIGMAR1MEN1KMT2AACHE
SCHEMBL5919572 0.75 BCHE (0.64) BCHEMCHR1SMN1; SMN2MEN1KMT2A
SCHEMBL13596972 0.75 BCHE (0.62) BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998047870-A1 PROCESS FOR THE SYNTHESIS OF 4-[6-(HEXYLCARBAMOYLOXY) HEXYLCARBAMOYLOXY]-PIPERIDINE-1- CARBOXYLIC ACID 4-PHENOXYPHENYL ESTER AMERICAN HOME PRODUCTS CORPORATION (US) 1998-10-29 WO disclosed