Pentachlorophenol

Pentachlorophenol

SCHEMBL8717856

C1CCC1.Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.77
HPGD P15428 6/20 0.77
HSD17B10 Q99714 6/20 0.77
MEN1 O00255 2/20 0.77
ALDH1A1 P00352 2/20 0.77
LMNA P02545 2/20 0.77
MAPT P10636 2/20 0.77
KMT2A Q03164 2/20 0.77
CYP1A2 P05177 4/20 0.46
CYP2C9 P11712 4/20 0.46
HIF1A Q16665 3/20 0.46
CASP1 P29466 1/20 0.42
CYP2C19 P33261 1/20 0.40
MAPK1 P28482 3/20 0.39
CYP3A4 P08684 3/20 0.36
USP2 O75604 1/20 0.36
TP53 P04637 1/20 0.36
GLA P06280 1/20 0.36
THRB P10828 1/20 0.36
ALOX15 P16050 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pentachlorophenol SCHEMBL5845375 1.00 TSHR (0.77) TSHRHPGDHSD17B10MEN1ALDH1A1
Pentachlorophenol SCHEMBL5341373 0.90 TSHR (0.62) TSHRHPGDHSD17B10MEN1ALDH1A1
Pentachlorophenol SCHEMBL1330735 0.88 HSD17B10 (1.00) TSHRHPGDHSD17B10MEN1ALDH1A1
Pentachlorophenol SCHEMBL5315995 0.88 HSD17B10 (1.00) TSHRHPGDHSD17B10MEN1ALDH1A1
Pentachlorophenol SCHEMBL1492 0.88 HSD17B10 (1.00) TSHRHPGDHSD17B10MEN1ALDH1A1
Pentachlorophenol SCHEMBL23121452 0.88 HSD17B10 (1.00) TSHRHPGDHSD17B10MEN1ALDH1A1
Pentachlorophenol SCHEMBL22027593 0.84 HSD17B10 (0.91) TSHRHPGDHSD17B10MEN1ALDH1A1
Pentachlorophenol SCHEMBL11459279 0.84 HSD17B10 (0.91) TSHRHPGDHSD17B10MEN1ALDH1A1
Pentachlorophenol SCHEMBL21647360 0.84 HSD17B10 (0.91) TSHRHPGDHSD17B10MEN1ALDH1A1
Pentachlorophenol SCHEMBL21177789 0.84 HSD17B10 (0.91) TSHRHPGDHSD17B10MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103003288-B Oligonucleotide analogues with modified intersubunit linkages and/or terminal groups 萨勒普塔医疗公司 2019-06-21 CN disclosed
CN-108864192-A Function modified oligonucleotides and its subunit 萨勒普塔医疗公司 2018-11-23 CN disclosed
EP-0876205-A1 PARTICLES HAVING A POLYMERIC SHELL AND THEIR PRODUCTION Ciba Specialty Chemicals Water Treatments Limited (GB) 1998-11-11 EP disclosed
WO-1997024179-A1 PARTICLES HAVING A POLYMERIC SHELL AND THEIR PRODUCTION ALLIED COLLOIDS LIMITED (GB) 1997-07-10 WO disclosed