SCHEMBL871833

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL871834	1.00	PDE4B (0.48)	PDE4BEGFRERBB2KDM4ESMN1; SMN2
	SCHEMBL870760	0.93	NPC1 (0.45)	PDE4BEGFRERBB2KDM4ESMN1; SMN2
	SCHEMBL870761	0.93	NPC1 (0.45)	PDE4BEGFRERBB2KDM4ESMN1; SMN2
	SCHEMBL869488	0.86	PDE4B (0.51)	PDE4BEGFRKDM4ESMN1; SMN2HSD17B10
	SCHEMBL869489	0.86	PDE4B (0.51)	PDE4BEGFRKDM4ESMN1; SMN2HSD17B10
	SCHEMBL870832	0.81	PDE4B (0.51)	PDE4BKDM4ESMN1; SMN2HSD17B10
	SCHEMBL870833	0.81	PDE4B (0.51)	PDE4BKDM4ESMN1; SMN2HSD17B10
	SCHEMBL8177936	0.80	PDE4B (0.48)	PDE4BEGFRKDM4ESMN1; SMN2HSD17B10
	SCHEMBL870222	0.80	PDE4B (0.50)	PDE4BEGFR
	SCHEMBL870221	0.80	PDE4B (0.50)	PDE4BEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.