SCHEMBL871855

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3026093	1.00	PDE4B (0.45)	PDE4BHPGDSPDE4DPDE4APDE4C
	SCHEMBL871134	0.91	PDE4B (0.46)	PDE4BHPGDSPDE4DPDE4APDE4C
	SCHEMBL3016921	0.91	PDE4B (0.46)	PDE4BHPGDSPDE4DPDE4APDE4C
	SCHEMBL871372	0.90	PDE4B (0.43)	PDE4BHPGDSPDE4DTTKTNKS
	SCHEMBL3022897	0.90	PDE4B (0.43)	PDE4BHPGDSPDE4DTTKTNKS
	SCHEMBL870787	0.90	PDE4B (0.46)	PDE4BHPGDSPDE4DPDE4APDE4C
	SCHEMBL870786	0.90	PDE4B (0.46)	PDE4BHPGDSPDE4DPDE4APDE4C
	SCHEMBL870054	0.90	PDE4B (0.47)	PDE4BHPGDSPDE4DPDE4APDE4C
	SCHEMBL872524	0.90	PDE4B (0.43)	PDE4BHPGDSPDE4DTNKSCNR1
	SCHEMBL3030939	0.90	PDE4B (0.43)	PDE4BHPGDSPDE4DTNKSCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.