Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | GFER | P55789 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718594 | 1.00 | MAPT (0.50) | MAPTGAAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL14438098 | 1.00 | MAPT (0.50) | MAPTGAAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL765856 | 0.79 | GAA (0.52) | MAPTGAAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL20335404 | 0.77 | MEN1 (0.50) | MAPTGAAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL13188669 | 0.77 | GAA (0.51) | MAPTGAAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL8221412 | 0.77 | NOX1 (0.34) | MAPTGAAALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1002644 | 0.77 | NOX1 (0.34) | MAPTGAAALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28527555 | 0.77 | MEN1 (0.50) | MAPTGAAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1002645 | 0.77 | NOX1 (0.34) | MAPTGAAALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL19918085 | 0.77 | MEN1 (0.50) | MAPTGAAALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567982-B1 | Azole compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5466820-A | Fungicides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-11-14 | — | — | US | disclosed |
| US-5371101-A | Fungicides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| EP-0567982-A1 | Azole compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1993-11-03 | — | — | EP | disclosed |