Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 6/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6550566 | 0.89 | ATM (0.47) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL7799297 | 0.86 | ATM (0.42) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL8722389 | 0.86 | ATM (0.41) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL3338973 | 0.82 | TSHR (0.62) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL2427216 | 0.81 | ATM (0.46) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL22092322 | 0.79 | ATM (0.50) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL9644232 | 0.79 | ATM (0.38) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL7878196 | 0.79 | ATM (0.43) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL109750 | 0.79 | ATM (0.79) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL109751 | 0.79 | ATM (0.79) | ATMHCAR2MAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834396-A | THE DYE-CONTAINING LAYER/SUBSTRATE HAVING A HEAT- AND FRICTION-RESISTANT TOP LAYER; ANTISOILANTS AND -STICKING AGENTS; RESOLUTION; PRINTERS AND COPIERS USING AN N-TIMES SPEED MODE; STORAGE STABILITY | RICOH COMPANY, LTD. (JP) | 1998-11-10 | — | — | US | disclosed |