SCHEMBL871887

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8187441	1.00	USP30 (0.37)	USP30HTR1AHTR7DHFRCYP1A2
	SCHEMBL871888	1.00	USP30 (0.37)	USP30HTR1AHTR7DHFRCYP1A2
	SCHEMBL869967	0.90	CYP1A2 (0.37)	CYP1A2CYP3A4ALDH1A1POLBNPSR1
	SCHEMBL869968	0.90	CYP1A2 (0.37)	CYP1A2CYP3A4ALDH1A1POLBNPSR1
	Hydrochloric Acid SCHEMBL870845	0.89	CYP1A2 (0.37)	CYP1A2CYP3A4ALDH1A1POLBNPSR1
	Hydrochloric Acid SCHEMBL870846	0.89	CYP1A2 (0.37)	CYP1A2CYP3A4ALDH1A1POLBNPSR1
	SCHEMBL3030781	0.87	PDE4B (0.40)	KCNH2PDE4BPDE4D
	SCHEMBL3030776	0.87	PDE4B (0.40)	KCNH2PDE4BPDE4D
	SCHEMBL8170051	0.86	KCNH2 (0.38)	USP30DHFRCYP1A2CYP3A4KCNH2
	SCHEMBL870246	0.85	RIPK2 (0.35)	HTR1AHTR7CYP1A2CYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.