Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29458149 | 0.90 | CYP2A6 (0.54) | HPRT1TSHRCYP2A6CYP1A2ALDH1A1 | |
| SCHEMBL272576 | 0.90 | CYP2A6 (0.54) | HPRT1TSHRCYP2A6CYP1A2ALDH1A1 | |
| SCHEMBL29785159 | 0.89 | CYP2A6 (0.52) | HPRT1TSHRCYP2A6CYP1A2ALDH1A1 | |
| SCHEMBL15845323 | 0.81 | HPRT1 (0.52) | HPRT1TSHRCYP2A6CYP1A2ALDH1A1 | |
| SCHEMBL1588479 | 0.79 | HPRT1 (0.54) | HPRT1TSHRCYP2A6CYP1A2ALDH1A1 | |
| SCHEMBL8712215 | 0.79 | HPRT1 (0.48) | HPRT1TSHRCYP2A6CYP1A2ALDH1A1 | |
| SCHEMBL31236201 | 0.78 | CYP1A2 (0.42) | TSHRCYP2A6CYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL8714687 | 0.78 | CYP1A2 (0.42) | TSHRCYP2A6CYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL8713224 | 0.76 | HPRT1 (0.45) | HPRT1TSHRCYP2A6ALDH1A1HSD17B10 | |
| SCHEMBL8546922 | 0.75 | HPRT1 (0.48) | HPRT1TSHRCYP2A6CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35773-E | SILOXANE-ADDITION POLYMER COMPOSITE | NIPPON SHOKUBAI CO., LTD. (JP) | 1998-04-21 | — | — | US | disclosed |
| US-5558803-A | ADDITION-CONDENSATION GRAFT COPOLYMERS FOR DIELECTRIC PARTICLES AND INSULATING LIQUIDS | NIPPON SHOKUBAI CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| US-5376294-A | A dielectric particle and a polysiloxane/acrylic ester additive in a dielectric dispersant medium; large shear stress and low current density; stability; nonsettling | NIPPON SHOKUBAI CO., LTD. (JP) | 1994-12-27 | — | — | US | disclosed |
| EP-0529166-A1 | Electrorheological fluids | NIPPON SHOKUBAI CO., LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |