⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4265250 | 0.82 | CARM1 (0.30) | — | |
| SCHEMBL4254581 | 0.82 | CARM1 (0.30) | — | |
| SCHEMBL4254586 | 0.82 | CARM1 (0.30) | — | |
| SCHEMBL18913927 | 0.67 | — | — | |
| SCHEMBL4878612 | 0.65 | — | — | |
| SCHEMBL8721670 | 0.65 | — | — | |
| SCHEMBL14167745 | 0.63 | HTT (0.33) | — | |
| SCHEMBL14885162 | 0.63 | CARM1 (0.30) | — | |
| SCHEMBL23664665 | 0.60 | — | — | |
| SCHEMBL22703930 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606382-B1 | 1,8-BENZONAPHTHYRIDINE DERIVATIVES AND ANTIMICROBIAL COMPOSITIONS | BELLON LABOR SA ROGER (FR) | 1998-05-13 | — | — | EP | disclosed |
| EP-0606382-A1 | 1,8-BENZONAPHTHYRIDINE DERIVATIVES AND ANTIMICROBIAL COMPOSITIONS | LABORATOIRE ROGER BELLON (FR) | 1994-07-20 | — | — | EP | disclosed |
| WO-1993007144-A1 | 1,8-BENZONAPHTHYRIDINE DERIVATIVES AND ANTIMICROBIAL COMPOSITIONS | LABORATOIRE ROGER BELLON (FR) | 1993-04-15 | — | — | WO | disclosed |
| EP-0536035-A1 | 1,8-Benzonaphthyridine derivatives and antimicrobial compositions | LABORATOIRE ROGER BELLON (FR) | 1993-04-07 | — | — | EP | disclosed |