SCHEMBL871946

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL871947	1.00	ACVR1 (0.40)	ACVR1PDE4BMCHR1CHRM1HTR2A
	SCHEMBL3029083	0.95	ACVR1 (0.40)	ACVR1PDE4BVCPCNR2HDAC1
	SCHEMBL3029088	0.95	ACVR1 (0.40)	ACVR1PDE4BVCPCNR2HDAC1
	SCHEMBL871756	0.94	ACVR1 (0.40)	ACVR1PDE4BVCPCNR2HDAC1
	SCHEMBL871755	0.94	ACVR1 (0.40)	ACVR1PDE4BVCPCNR2HDAC1
	SCHEMBL870990	0.93	ACKR3 (0.41)	ACVR1PDE4BVCPCNR2HDAC1
	SCHEMBL3016547	0.92	ACKR3 (0.41)	ACVR1PDE4BVCPHDAC1ACKR3
	SCHEMBL870893	0.91	PDE4B (0.41)	ACVR1PDE4BCNR2HDAC1ACKR3
	SCHEMBL870892	0.91	PDE4B (0.41)	ACVR1PDE4BCNR2HDAC1ACKR3
	SCHEMBL871760	0.91	ACVR1 (0.38)	ACVR1PDE4BVCPCNR2HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.