Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304323 | 0.86 | F2 (0.44) | F2 | |
| SCHEMBL8947600 | 0.81 | F2 (0.54) | F2 | |
| Hydrochloric Acid SCHEMBL8947735 | 0.80 | F2 (0.54) | F2 | |
| SCHEMBL7304313 | 0.76 | F2 (0.55) | F2 | |
| SCHEMBL7300995 | 0.76 | F2 (0.43) | F2 | |
| SCHEMBL9169944 | 0.74 | F2 (0.55) | F2 | |
| SCHEMBL8717101 | 0.74 | F2 (0.33) | F2F10PLGPLATPRSS1 | |
| SCHEMBL7298712 | 0.73 | F2 (0.50) | F2 | |
| SCHEMBL7306791 | 0.73 | F2 (0.41) | F2PLGPLAT | |
| SCHEMBL7299001 | 0.71 | F2 (0.69) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763604-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | disclosed |
| US-5677448-A | CHEMICAL INTERMEDIATES FOR MAKING ANTAGONIST OF THROMBIN, TREATING THROMBOSIS, STROKE, INFLAMMATION, ARTERIOSCLEROSIS, CARDIOVASCULAR DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1997-10-14 | — | — | US | disclosed |