Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 15/20 | 0.43 |
| ▸ | HPN | P05981 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947640 | 0.90 | F2 (0.53) | F2HPNST14 | |
| SCHEMBL8719639 | 0.90 | F2 (0.53) | F2HPNST14 | |
| Acetic Acid SCHEMBL8947636 | 0.83 | F2 (0.54) | F2HPNST14 | |
| SCHEMBL8947623 | 0.80 | F2 (0.48) | F2 | |
| Hydrochloric Acid SCHEMBL8947789 | 0.77 | F2 (0.61) | F2 | |
| Hydrochloric Acid SCHEMBL8947676 | 0.77 | F2 (0.61) | F2 | |
| Hydrochloric Acid SCHEMBL8947627 | 0.77 | F2 (0.61) | F2 | |
| SCHEMBL7298133 | 0.77 | F2 (0.53) | F2 | |
| Acetic Acid SCHEMBL8721719 | 0.77 | F2 (0.56) | F2 | |
| Hydrochloric Acid SCHEMBL8719690 | 0.76 | F2 (0.59) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763604-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | disclosed |
| US-5677448-A | CHEMICAL INTERMEDIATES FOR MAKING ANTAGONIST OF THROMBIN, TREATING THROMBOSIS, STROKE, INFLAMMATION, ARTERIOSCLEROSIS, CARDIOVASCULAR DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1997-10-14 | — | — | US | disclosed |
| US-5578594-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-11-26 | — | — | US | disclosed |
| US-5405854-A | Anticoagulants | HOFFMANN-LA ROCHE INC. (US) | 1995-04-11 | — | — | US | disclosed |