SCHEMBL8719959

SCHEMBL8719959

CC(=O)ON(Cc1ccccc1)C(=O)C(CC(=O)NCC1CCN(C(=N)N)CC1)NS(=O)(=O)c1ccc2ccccc2c1

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
F2 P00734 17/20 0.59
PLAU P00749 4/20 0.51
F10 P00742 3/20 0.51
PLG P00747 2/20 0.51
ST14 Q9Y5Y6 2/20 0.51
PLAT P00750 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8947777 0.86 F2 (0.59) F2PLAUF10PLGST14
Hydrochloric Acid SCHEMBL8947724 0.86 F2 (0.59) F2PLAUF10PLGST14
SCHEMBL8716837 0.83 F2 (0.66) F2PLAUF10PLGST14
SCHEMBL8947770 0.83 F2 (0.63) F2
Hydrochloric Acid SCHEMBL8947767 0.82 F2 (0.61) F2
Hydrochloric Acid SCHEMBL8947567 0.81 F2 (0.63) F2
SCHEMBL8947760 0.81 F2 (0.65) F2
Hydrochloric Acid SCHEMBL8947694 0.81 F2 (0.58) F2
SCHEMBL8717349 0.80 F2 (0.65) F2PLAUF10PLGST14
SCHEMBL8717274 0.80 F2 (0.72) F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5763604-A ANTICOAGULANTS HOFFMANN-LA ROCHE INC. (US) 1998-06-09 US disclosed