Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.60 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2658540 | 0.88 | TAAR1 (0.64) | TAAR1SLC7A5MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL22458056 | 0.88 | TAAR1 (0.64) | TAAR1SLC7A5MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL1279049 | 0.88 | TAAR1 (0.64) | TAAR1SLC7A5MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL17281 | 0.86 | TAAR1 (0.60) | TAAR1SLC7A5MTNR1AMTNR1BIDO1 | |
| SCHEMBL17280 | 0.86 | TAAR1 (0.60) | TAAR1SLC7A5MTNR1AMTNR1BIDO1 | |
| SCHEMBL31506228 | 0.86 | TAAR1 (0.60) | TAAR1SLC7A5MTNR1AMTNR1BIDO1 | |
| SCHEMBL19943588 | 0.85 | TAAR1 (0.68) | TAAR1SLC7A5MTNR1AMTNR1BIDO1 | |
| SCHEMBL146611 | 0.84 | TAAR1 (0.66) | TAAR1SLC7A5CYP1A2 | |
| SCHEMBL29855157 | 0.84 | TAAR1 (0.66) | TAAR1SLC7A5CYP1A2 | |
| SCHEMBL4596077 | 0.84 | TAAR1 (0.66) | TAAR1SLC7A5CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763604-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | disclosed |