SCHEMBL8720472

SCHEMBL8720472

CCCCCCOc1ccc2c(ccc3c(F)c(OCCCC[Si](C)(C)CCCC)ccc32)n1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 2/20 0.34
MAPT P10636 1/20 0.34
S1PR5 Q9H228 2/20 0.32
S1PR1 P21453 1/20 0.32
MCHR1 Q99705 1/20 0.32
NCF1 P14598 1/20 0.32
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
SOAT1 P35610 1/20 0.32
ALDH1A1 P00352 3/20 0.31
HPGD P15428 2/20 0.31
KDM4E B2RXH2 2/20 0.31
ABCB11 O95342 1/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
GAA P10253 1/20 0.31
CYP2D6 P10635 1/20 0.31
SCN1A P35498 1/20 0.31
OPRK1 P41145 1/20 0.31
KCNH2 Q12809 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8720136 0.92 TLR8 (0.39) TLR8MAPTMCHR1NCF1CNR1
SCHEMBL8722724 0.92 TLR8 (0.39) TLR8MAPTMCHR1NCF1CNR1
SCHEMBL8905326 0.92 TLR8 (0.39) TLR8MAPTMCHR1NCF1CNR1
SCHEMBL8719419 0.92 TLR8 (0.39) TLR8MAPTMCHR1NCF1CNR1
SCHEMBL8724265 0.92 TLR8 (0.39) TLR8MAPTMCHR1NCF1CNR1
SCHEMBL8720299 0.92 TLR8 (0.39) TLR8MAPTMCHR1NCF1CNR1
SCHEMBL8720141 0.92 TLR8 (0.39) TLR8MAPTMCHR1NCF1CNR1
SCHEMBL8720125 0.92 TLR8 (0.39) TLR8MAPTMCHR1NCF1CNR1
SCHEMBL8723136 0.92 TLR8 (0.39) TLR8MAPTMCHR1NCF1CNR1
SCHEMBL8722600 0.92 TLR8 (0.39) TLR8MAPTMCHR1NCF1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0839173-A1 FERROELECTRIC LIQUID CRYSTAL MIXTURE Hoechst Research & Technology Deutschland GmbH & Co. KG (DE) 1998-05-06 EP disclosed