SCHEMBL872079

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL872080	1.00	PDE4B (0.44)	PDE4BUTS2RPRKAA2KDM4ESMN1; SMN2
	SCHEMBL871827	0.95	PDE4B (0.46)	PDE4BPRKAA2KDM4ESMN1; SMN2HSD17B10
	SCHEMBL871826	0.95	PDE4B (0.46)	PDE4BPRKAA2KDM4ESMN1; SMN2HSD17B10
	SCHEMBL524053	0.92	PDE4B (0.52)	PDE4BPRKAA2KDM4ESMN1; SMN2HSD17B10
	SCHEMBL870077	0.92	PDE4B (0.52)	PDE4BPRKAA2KDM4ESMN1; SMN2HSD17B10
	SCHEMBL524054	0.92	PDE4B (0.52)	PDE4BPRKAA2KDM4ESMN1; SMN2HSD17B10
	SCHEMBL871936	0.92	PDE4B (0.40)	PDE4BUTS2RPRKAA2KDM4ESMN1; SMN2
	SCHEMBL10221938	0.89	PDE4B (0.55)	PDE4B
	SCHEMBL869880	0.89	PDE4B (0.42)	PDE4BPRKAA2KDM4ESMN1; SMN2HSD17B10
	SCHEMBL871650	0.88	PDE4B (0.45)	PDE4BPRKAA2KDM4ESMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.