Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 9/20 | 0.38 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1888283 | 0.91 | CA1 (0.50) | CA1CA2CA7CA12CA14 | |
| SCHEMBL2318522 | 0.91 | CA1 (0.50) | CA1CA2CA7CA12CA14 | |
| SCHEMBL1888284 | 0.91 | CA1 (0.50) | CA1CA2CA7CA12CA14 | |
| Hydrochloric Acid SCHEMBL3606870 | 0.89 | CA1 (0.49) | CA1CA2CA7CA12CA14 | |
| SCHEMBL4327755 | 0.84 | KMT2A (0.46) | CA1CA2CA7CA12CA14 | |
| SCHEMBL9136842 | 0.84 | KMT2A (0.46) | CA1CA2CA7CA12CA14 | |
| SCHEMBL4327766 | 0.84 | KMT2A (0.46) | CA1CA2CA7CA12CA14 | |
| SCHEMBL13804888 | 0.79 | CA1 (0.42) | CA1CA2CA7CA12CA14 | |
| SCHEMBL875372 | 0.77 | CA1 (0.47) | CA1CA2CA7CA12CA14 | |
| SCHEMBL29395538 | 0.77 | CA12 (0.47) | CA1CA2CA7CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801655-B1 | BASIC PROLINE-AMIDE DERIVATIVES OF GE 2270 AND GE 2270-LIKE ANTIBIOTICS | BIOSEARCH ITALIA SPA (IT) | 1998-04-15 | — | — | EP | disclosed |