Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 19/20 | 0.52 |
| ▸ | HTR1B | P28222 | 16/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | HTR1F | P30939 | 2/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30909270 | 1.00 | HTR1D (0.52) | HTR1DHTR1BHTR1AHTR1FCHRM2 | |
| SCHEMBL30908857 | 0.97 | HTR1D (0.51) | HTR1DHTR1BHTR1AHTR1FCHRM2 | |
| SCHEMBL8721066 | 0.87 | HTR1D (0.55) | HTR1DHTR1BHTR1AHTR1FCHRM2 | |
| SCHEMBL7480770 | 0.85 | HTR1D (0.61) | HTR1DHTR1BHTR1AHTR1FCHRM2 | |
| SCHEMBL8386457 | 0.85 | HTR1D (0.52) | HTR1DHTR1BHTR1AHTR1FCHRM2 | |
| SCHEMBL30909136 | 0.82 | HTR1D (0.46) | HTR1DHTR1BHTR1AHTR1FCHRM2 | |
| SCHEMBL8383579 | 0.82 | HTR1D (0.46) | HTR1DHTR1BHTR1AHTR1FCHRM2 | |
| SCHEMBL8721021 | 0.82 | HTR1D (0.47) | HTR1DHTR1BHTR1AHTR1FCHRM2 | |
| SCHEMBL8721860 | 0.81 | HTR1D (0.49) | HTR1DHTR1BHTR1AHTR1F | |
| SCHEMBL8720670 | 0.81 | HTR1D (0.49) | HTR1DHTR1BHTR1AHTR1FCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0875513-A1 | Substituted heteroaromatic 5-HT 1F agonists | ELI LILLY AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |