Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 13/20 | 0.49 |
| ▸ | HTR1B | P28222 | 11/20 | 0.49 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | HTR1F | P30939 | 2/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30909155 | 1.00 | HTR1D (0.49) | HTR1DHTR1BHTR1AHTR1FRORC | |
| SCHEMBL8381537 | 0.93 | HTR1D (0.47) | HTR1DHTR1BHTR1AHTR1FRORC | |
| SCHEMBL8720670 | 0.93 | HTR1D (0.49) | HTR1DHTR1BHTR1AHTR1FRORC | |
| SCHEMBL8382857 | 0.91 | HTR1D (0.48) | HTR1DHTR1BHTR1AHTR1FRORC | |
| SCHEMBL7489592 | 0.86 | HTR1D (0.54) | HTR1DHTR1BHTR1AHTR1FRORC | |
| SCHEMBL8721064 | 0.86 | HTR1D (0.48) | HTR1DHTR1BHTR1AHTR1FRORC | |
| SCHEMBL8721860 | 0.85 | HTR1D (0.49) | HTR1DHTR1BHTR1AHTR1FSLC6A4 | |
| SCHEMBL7489363 | 0.85 | HTR1D (0.52) | HTR1DHTR1BHTR1AHTR1FRORC | |
| SCHEMBL30908936 | 0.85 | HTR1D (0.52) | HTR1DHTR1BHTR1AHTR1FRORC | |
| SCHEMBL8721021 | 0.83 | HTR1D (0.47) | HTR1DHTR1BHTR1AHTR1FRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0875513-A1 | Substituted heteroaromatic 5-HT 1F agonists | ELI LILLY AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |