Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26698338 | 0.92 | MAPT (0.53) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL9109948 | 0.78 | TSHR (0.53) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL9913603 | 0.78 | TSHR (0.56) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL10574972 | 0.77 | MEN1 (0.46) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL12302266 | 0.74 | TSHR (0.51) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL10248783 | 0.73 | MAPT (0.49) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL22992491 | 0.69 | MAPT (0.44) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL26698344 | 0.68 | INPPL1 (0.36) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL11026382 | 0.68 | ESR1 (0.42) | ALDH1A1L3MBTL1 | |
| 4-Chloro-2-Nitroaniline SCHEMBL131251 | 0.68 | TDP1 (0.64) | MAPTMEN1KMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572852-B1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF AG (DE) | 1998-10-21 | — | — | EP | disclosed |
| EP-0572852-A1 | Quinoxalin-2,3(1H,4H)-diones used as medicine | BASF Aktiengesellschaft (DE) | 1993-12-08 | — | — | EP | disclosed |