SCHEMBL872419

SCHEMBL872419

C=Cc1ccnc(C=C)n1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 1/20 0.33
GRM4 Q14833 1/20 0.31
S1PR4 O95977 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6887027 0.79
SCHEMBL28022279 0.76
SCHEMBL1982143 0.74
SCHEMBL9159764 0.74
SCHEMBL4024375 0.74
SCHEMBL8270697 0.74
SCHEMBL12805217 0.74
SCHEMBL16123466 0.74
SCHEMBL21645064 0.74
SCHEMBL20216218 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106433135-A Curable rubber composition and curable rubber 黄品超 2017-02-22 CN claimed
EP-4704916-A1 MODIFIED ANTIBODIES, ANTIBODY FRAGMENTS THEREOF, AND ANTIBODY-DRUG CONJUGATES Innovent Biologics (Suzhou) Co., Ltd. (CN) 2026-03-11 EP disclosed
EP-4648799-A1 LIGAND-DRUG CONJUGATES Sun Pharma Advanced Research Company Ltd (IN) 2025-11-19 EP disclosed
CN-120058585-A Dimercapto conjugate of active allyl alcohol acetate, and preparation method and application thereof 南京工业大学 2025-05-30 CN disclosed
WO-2025103474-A1 DOUBLE-TOXIN ANTIBODY-DRUG CONJUGATE AND USE THEREOF 成都康弘生物科技有限公司 2025-05-22 WO disclosed
CN-120019819-A Double toxin antibody drug conjugate and application thereof 成都康弘生物科技有限公司 2025-05-20 CN disclosed
CN-119455000-A Triazine compound, conjugate thereof, preparation method and application 四川科伦博泰生物医药股份有限公司 2025-02-18 CN disclosed
CN-119431181-A Di-ene linker, linker-drug conjugate, antibody-conjugated drug and uses thereof 泰诚思(上海)生物医药有限公司 2025-02-14 CN disclosed
CN-119318715-A Anti-PD-L1 and Anti-HER2 diabody oriented nano-drug system and preparation method and application thereof 江苏大学 2025-01-17 CN disclosed
EP-4486775-A2 THERAPEUTIC ANTIBODIES Cambridge Enterprise Limited (GB) 2025-01-08 EP disclosed
WO-2023166318-A2 THERAPEUTIC ANTIBODIES CAMBRIDGE ENTERPRISE LIMITED (GB) 2023-09-07 WO disclosed
WO-2022223783-A9 THIOL-CONJUGATION WITH UNSATURATED PHOSPHORUS(V) COMPOUNDS FORSCHUNGSVERBUND BERLIN E.V. (DE) 2023-03-02 WO disclosed
CN-115666653-A Antibody-drug conjugates 斯皮雷亚有限公司 2023-01-31 CN disclosed
CN-106433135-A Curable rubber composition and curable rubber 黄品超 2017-02-22 CN disclosed
US-20130287700-A1 COMPOUNDS FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISORDERS ON THE OLFACTORY EPITHELIUM KLINIKUM DARMSTADT GMBH (DE) 2013-10-31 US disclosed
EP-2619590-A2 COMPOUNDS FOR DIAGNOSING NEURODEGENERATIVE DISEASES AT THE RETINA Technische Universität Darmstadt (DE) 2013-07-31 EP disclosed
EP-2619591-A2 COMPOUNDS FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISORDERS ON THE OLFACTORY EPITHELIUM Technische Universität Darmstadt (DE) 2013-07-31 EP disclosed
WO-2012041292-A2 COMPOUNDS FOR DIAGNOSING NEURODEGENERATIVE DISEASES AT THE RETINA KLINIKUM DARMSTADT GMBH (DE) 2012-04-05 WO disclosed
WO-2012037928-A2 COMPOUNDS FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISORDERS ON THE OLFACTORY EPITHELIUM KLINIKUM DARMSTADT GMBH (DE) 2012-03-29 WO disclosed
US-5439950-A Intraocular lenses KABI PHARMACIA OPHTHALMICS, INC. (US) 1995-08-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130287700-A1 COMPOUNDS FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISORDERS ON THE OLFACTORY EPITHELIUM SNCA, MAPT, TARDBP HDAC8 4540/4885GRM4 1348/4885S1PR4 3344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.