Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8724254 | 1.00 | HTR2A (0.38) | HTR2AHTR2CGRM2ALDH1A1SMN1; SMN2 | |
| SCHEMBL7739032 | 0.87 | HTR2A (0.38) | HTR2AHTR2CGRM2MAOAMAOB | |
| SCHEMBL7739030 | 0.87 | HTR2A (0.38) | HTR2AHTR2CGRM2MAOAMAOB | |
| SCHEMBL9447515 | 0.80 | HTR2A (0.36) | HTR2AHTR2C | |
| SCHEMBL9447524 | 0.80 | HTR2A (0.36) | HTR2AHTR2C | |
| SCHEMBL12736008 | 0.78 | SLC6A4 (0.51) | HTR2AHTR2CSLC6A2SLC6A4 | |
| SCHEMBL10490787 | 0.77 | DRD4 (0.40) | GRM2SLC6A2SLC6A4DRD2KMT2A | |
| SCHEMBL10490794 | 0.77 | DRD4 (0.40) | GRM2SLC6A2SLC6A4DRD2KMT2A | |
| SCHEMBL7753241 | 0.74 | MAOB (0.53) | TSHRMAOAMAOBBACE1CYP19A1 | |
| SCHEMBL7753238 | 0.74 | MAOB (0.53) | TSHRMAOAMAOBBACE1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792386-A | A MIXTURE OF ALKYLCYCLOHEXYL(PHENYLENE)DIFLUROMETHOXY-BENZENES AND FLUORO-CONTAINING COMPOUNDS; LOW VISCOSITY; LOW TEMPERATURE MISCIBILITY; HEAT AND CHEMICAL RESISTANCE; ACTIVE MATRIX | CHISSO CORPORATION (JP) | 1998-08-11 | — | — | US | disclosed |
| US-5728319-A | Liquid crystal composition and liquid crystal display device | CHISSO CORPORATION (JP) | 1998-03-17 | — | — | US | disclosed |