SCHEMBL8724311

SCHEMBL8724311

CCCCCCOc1ccc2c(ccc3cc(OCCCCCC)ccc32)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.55
TSHR P16473 2/20 0.53
THRA P10827 1/20 0.52
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA3 P07451 1/20 0.49
CA4 P22748 1/20 0.49
CA6 P23280 1/20 0.49
CA7 P43166 1/20 0.49
CA9 Q16790 1/20 0.49
CA14 Q9ULX7 1/20 0.49
CA5B Q9Y2D0 1/20 0.49
LTA4H P09960 2/20 0.49
TP53 P04637 2/20 0.49
PLA2G4B P0C869 1/20 0.47
MTNR1A P48039 1/20 0.47
HTR1A P08908 2/20 0.47
HTR1D P28221 2/20 0.47
HTR1B P28222 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12259989 0.98 NR5A1 (0.53) NR5A1TSHRTHRACA12CA1
SCHEMBL12259997 0.98 NR5A1 (0.53) NR5A1TSHRTHRACA12CA1
SCHEMBL12278287 0.98 NR5A1 (0.53) NR5A1TSHRTHRACA12CA1
SCHEMBL16519478 0.92 CA12 (0.51) NR5A1THRACA12CA1CA2
SCHEMBL4945033 0.92 NR5A1 (0.62) NR5A1TSHRTHRACA12CA1
SCHEMBL347683 0.92 NR5A1 (0.62) NR5A1TSHRTHRACA12CA1
SCHEMBL10642885 0.92 NR5A1 (0.62) NR5A1TSHRTHRACA12CA1
SCHEMBL12405208 0.91 NR5A1 (0.46) NR5A1TSHRTHRACA12CA1
SCHEMBL12405209 0.91 NR5A1 (0.46) NR5A1TSHRTHRACA12CA1
SCHEMBL7668477 0.91 PPM1A (0.53) NR5A1TSHRTHRACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-52131565-A None JP disclosed
EP-0839173-A1 FERROELECTRIC LIQUID CRYSTAL MIXTURE Hoechst Research & Technology Deutschland GmbH & Co. KG (DE) 1998-05-06 EP disclosed
WO-1997004039-A1 FERROELECTRIC LIQUID CRYSTAL MIXTURE HOECHST RESEARCH & TECHNOLOGY DEUTSCHLAND GMBH & CO. KG (DE) 1997-02-06 WO disclosed
JP-S52131565-A 2,7-DIALKOXYPHENANTHRENES AND PREPARATION OF SAME NIPPON STEEL CHEM CO LTD 1977-11-04 JP disclosed