Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8752728 | 0.92 | PDE2A (0.32) | DHODHPDE2A | |
| SCHEMBL8752743 | 0.91 | DHODH (0.36) | DHODHPDE2AALDH1A1HPGDMEN1 | |
| SCHEMBL8492504 | 0.85 | DHODH (0.35) | DHODHPDE2AALDH1A1HPGDMEN1 | |
| SCHEMBL8752744 | 0.85 | DHODH (0.32) | DHODHPDE2AMEN1KMT2A | |
| SCHEMBL7574528 | 0.85 | DHODH (0.31) | DHODH | |
| SCHEMBL8492889 | 0.84 | PDE2A (0.36) | DHODHPDE2AALDH1A1MAPTHPGD | |
| SCHEMBL8492849 | 0.84 | DHODH (0.36) | DHODHPDE2AALDH1A1HPGDMEN1 | |
| SCHEMBL7583005 | 0.83 | DHODH (0.32) | DHODHPDE2AMEN1KMT2A | |
| SCHEMBL7577256 | 0.83 | DHODH (0.32) | DHODHPDE2AMEN1KMT2A | |
| SCHEMBL9116657 | 0.83 | DHODH (0.40) | DHODHPDE2AALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0682659-B1 | 4-Benzoyl isoxazole derivatives, their preparation and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1997-04-16 | — | — | EP | claimed |
| EP-0682659-A1 | 4-BENZOYL ISOXAZOLES AND THEIR USE AS HERBICIDES. | RHONE POULENC AGRICULTURE (GB) | 1995-11-22 | — | — | EP | claimed |
| WO-1994018179-A1 | 4-BENZOYL ISOXAZOLES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LTD (GB) | 1994-08-18 | — | — | WO | claimed |
| CN-1083688-C | New herbicides | RHONE POULENC AGRICULTURE (GB) | 2002-05-01 | — | — | CN | disclosed |
| EP-0625508-B1 | Sulfur-containing derivatives of 2-cyano-1,3-diones and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1998-08-19 | — | — | EP | disclosed |
| EP-0682659-B1 | 4-Benzoyl isoxazole derivatives, their preparation and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1997-04-16 | — | — | EP | disclosed |
| EP-0682659-A1 | 4-BENZOYL ISOXAZOLES AND THEIR USE AS HERBICIDES. | RHONE POULENC AGRICULTURE (GB) | 1995-11-22 | — | — | EP | disclosed |
| CN-1104030-A | New herbicides | RHONE POULENC AGRICULTURE (GB) | 1995-06-28 | — | — | CN | disclosed |
| EP-0625508-A2 | Sulfur-containing derivatives of 2-cyano-1,3-diones and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-11-23 | — | — | EP | disclosed |
| WO-1994018179-A1 | 4-BENZOYL ISOXAZOLES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LTD (GB) | 1994-08-18 | — | — | WO | disclosed |