⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8724721 | 1.00 | — | — | |
| SCHEMBL727638 | 0.69 | — | — | |
| SCHEMBL6068360 | 0.69 | — | — | |
| SCHEMBL727639 | 0.69 | — | — | |
| SCHEMBL21457930 | 0.68 | — | — | |
| SCHEMBL4971559 | 0.67 | — | — | |
| SCHEMBL2494482 | 0.67 | — | — | |
| SCHEMBL14539912 | 0.67 | — | — | |
| SCHEMBL22115813 | 0.67 | — | — | |
| SCHEMBL2317874 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11964938-B2 | 3-phenyl-4-hexynoic acid derivatives as GPR40 agonists | CELON PHARMA S.A. (PL) | 2024-04-23 | — | — | US | disclosed |
| EP-3737470-B9 | 3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS | Celon Pharma Sa (PL) | 2024-03-13 | — | — | EP | disclosed |
| EP-3737470-B1 | 3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS | Celon Pharma Sa (PL) | 2022-12-14 | — | — | EP | disclosed |
| EP-3737470-B1 | 3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS | Celon Pharma Sa (PL) | 2022-12-14 | — | — | EP | disclosed |
| US-20200399198-A1 | 3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS | CELON PHARMA S.A. (PL) | 2020-12-24 | — | — | US | disclosed |
| WO-2019134984-A1 | 3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS | CELON PHARMA S.A. (PL) | 2019-07-11 | — | — | WO | disclosed |
| EP-2699581-B1 | 2-OXO-1-IMIDAZOLIDINYL IMIDAZOTHIADIAZOLE DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2015-11-25 | — | — | EP | disclosed |
| US-8957218-B2 | 2-oxo-1-imidazolidinyl imidazothiadiazole derivatives | UCB PHARMA S.A. (BE) | 2015-02-17 | — | — | US | disclosed |
| US-20140148489-A1 | 2-Oxo-1-Imidazolidinyl Imidazothiadiazole Derivatives | UCB PHARMA, S.A. (BE) | 2014-05-29 | — | — | US | disclosed |
| EP-2699581-A1 | 2-OXO-1-IMIDAZOLIDINYL IMIDAZOTHIADIAZOLE DERIVATIVES | UCB Pharma, S.A. (BE) | 2014-02-26 | — | — | EP | disclosed |
| WO-2012143117-A1 | 2-OXO-1-IMIDAZOLIDINYL IMIDAZOTHIADIAZOLE DERIVATIVES | UCB PHARMA, S.A. (BE) | 2012-10-26 | — | — | WO | disclosed |
| US-5837162-A | CYCLIC ETHERS FOR LIQUID CRYSTAL DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-17 | — | — | US | disclosed |
| US-5626793-A | Liquid-crystalline compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-05-06 | — | — | US | disclosed |
| WO-1993003113-A1 | LIQUID-CRYSTAL COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1993-02-18 | — | — | WO | disclosed |
| EP-0525140-A1 | LIQUID-CRYSTAL COMPOUNDS | MERCK PATENT GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |
| WO-1992013928-A1 | LIQUID-CRYSTAL COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1992-08-20 | — | — | WO | disclosed |