SCHEMBL872550

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL872551	1.00	KCNH2 (0.37)	KCNH2CKS1BSKP1SKP2PDE4B
	SCHEMBL4233037	0.90	PDE4B (0.36)	KCNH2PDE4BPDE4DPDE4APDE4C
	SCHEMBL4233040	0.90	PDE4B (0.36)	KCNH2PDE4BPDE4DPDE4APDE4C
	SCHEMBL871215	0.90	PDE4B (0.43)	KCNH2PDE4BPDE4DPDE4APDE4C
	SCHEMBL871214	0.90	PDE4B (0.43)	KCNH2PDE4BPDE4DPDE4APDE4C
	SCHEMBL10221633	0.89	CKS1B (0.42)	KCNH2CKS1BSKP1SKP2PDE4B
	SCHEMBL870811	0.89	CKS1B (0.42)	KCNH2CKS1BSKP1SKP2PDE4B
	SCHEMBL8168457	0.89	CKS1B (0.42)	KCNH2CKS1BSKP1SKP2PDE4B
	SCHEMBL870927	0.88	PDE4B (0.34)	KCNH2PDE4BPDE4DPDE4APDE4C
	SCHEMBL870928	0.88	PDE4B (0.34)	KCNH2PDE4BPDE4DPDE4APDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.