Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8373239 | 0.87 | SMN1; SMN2 (0.38) | MEN1KMT2ASMN1; SMN2CHRM5CHRM3 | |
| SCHEMBL1889483 | 0.87 | — | — | |
| SCHEMBL5617 | 0.87 | — | — | |
| SCHEMBL13667433 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL4078380 | 0.84 | SMN1; SMN2 (0.41) | MEN1KMT2ASMN1; SMN2CHRM5CHRM3 | |
| SCHEMBL28661173 | 0.84 | SMN1; SMN2 (0.37) | MEN1KMT2ASMN1; SMN2CHRM5CHRM3 | |
| SCHEMBL28291636 | 0.84 | SMN1; SMN2 (0.37) | MEN1KMT2ASMN1; SMN2CHRM5CHRM3 | |
| Ammonia Solution, Strong SCHEMBL17509976 | 0.84 | SMN1; SMN2 (0.37) | MEN1KMT2ASMN1; SMN2CHRM5CHRM3 | |
| Ethane SCHEMBL4260118 | 0.84 | SMN1; SMN2 (0.37) | MEN1KMT2ASMN1; SMN2CHRM5CHRM3 | |
| Morpholine SCHEMBL8429399 | 0.84 | MEN1 (0.61) | MEN1KMT2AKDM4EGAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998008839-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED THIOPHENE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |