SCHEMBL8725908

SCHEMBL8725908

CC(C)(SCC(=O)O)SCC(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 4/20 0.45
CYP2C19 P33261 3/20 0.45
HIF1A Q16665 2/20 0.45
HMGCR P04035 1/20 0.39
CHRM1 P11229 1/20 0.39
TBXA2R P21731 1/20 0.39
ADRA1A P35348 1/20 0.39
TSHR P16473 3/20 0.38
FFAR3 O14843 2/20 0.35
PHGDH O43175 1/20 0.35
GMNN O75496 1/20 0.34
TP53 P04637 1/20 0.34
POLB P06746 1/20 0.34
MAPT P10636 1/20 0.34
THRB P10828 1/20 0.34
CYP2C9 P11712 1/20 0.34
BLM P54132 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ALDH1A1 P00352 2/20 0.33
FFAR1 O14842 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22360390 0.86 CYP2D6 (0.35) CYP2D6CYP2C19HIF1AHMGCRCHRM1
SCHEMBL2223767 0.82
SCHEMBL6701234 0.82 CYP2D6 (0.45) CYP2D6CYP2C19HIF1AHMGCRCHRM1
SCHEMBL18805722 0.79 CYP2D6 (0.30) CYP2D6CYP2C19HIF1A
SCHEMBL9174852 0.78 CYP2D6 (0.41) CYP2D6CYP2C19HIF1AHMGCRCHRM1
SCHEMBL21600666 0.78 TSHR (0.52) CYP2D6CYP2C19HMGCRCHRM1TBXA2R
SCHEMBL27826986 0.74 CYP2D6 (0.43) CYP2D6CYP2C19HIF1AHMGCRCHRM1
SCHEMBL25659032 0.74 CYP2D6 (0.38) CYP2D6CYP2C19HIF1AHMGCRCHRM1
SCHEMBL13130591 0.72 HSD17B10 (0.38) CYP2D6CYP2C19HIF1AHMGCRCHRM1
SCHEMBL13129910 0.72 CYP2D6 (0.42) CYP2D6CYP2C19HIF1AHMGCRCHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119606914-B Macrophage bionic nano composite medicine and preparation method and application thereof SICHUAN UNIVERSITY (CN) 2026-05-26 CN claimed
CN-120114606-A Gelatin-based composite hydrogel microsphere and preparation method and application thereof 重庆大学 2025-06-10 CN claimed
CN-120078908-A Nanocomposite based on UCNPs-photosensitizer and preparation method and application thereof 上海新泊地新材料研究有限公司 2025-06-03 CN claimed
CN-119733061-A Bacterial outer membrane vesicle with synergistic effect of X-ray activated tumor immune metabolism regulation and pyrosis, and preparation method and application thereof 福州大学 2025-04-01 CN claimed
CN-119606914-A Macrophage bionic nano composite medicine and preparation method and application thereof 四川大学 2025-03-14 CN claimed
CN-119454596-A Preparation and application of ROS sensitive liposome nanoparticle (Qu@NPs) for mitochondrially delivering quercetin 江西中医药大学 2025-02-18 CN claimed
CN-118580491-A Active oxygen responsive polyamino acid coupled tyrosine kinase inhibitor and preparation method thereof 青岛大学 2024-09-03 CN claimed
CN-118290611-A Ethylene glycol chitosan-TK-doxorubicin copolymer and polymerization method and application thereof 湖州师范学院 2024-07-05 CN claimed
CN-114699537-B ROS response anticancer drug for improving curative effect of hypoxia-sensitized PD-1 antibody 西安交通大学医学院第一附属医院 2024-06-21 CN claimed
CN-117757453-A Neutral composite blocking remover and preparation method thereof 大庆市唯品科技开发有限公司 2024-03-26 CN claimed
CN-116019783-A Nanometer-temperature-sensitive assembled gel for nasal administration, preparation method and application thereof 中国医学科学院生物医学工程研究所 2023-04-28 CN claimed
CN-114081958-B Functionalized apoptosis small drug delivery system and preparation method and application thereof 中国医学科学院生物医学工程研究所 2023-04-25 CN claimed
CN-114306281-B Visual heterozygous cell membrane nano-delivery system and preparation method and application thereof 中国医学科学院生物医学工程研究所 2023-04-07 CN claimed
CN-114699537-A ROS (reactive oxygen species) -responsive anticancer drug for improving curative effect of hypoxia-sensitized PD-1 antibody 西安交通大学医学院第一附属医院 2022-07-05 CN claimed
US-20220169725-A1 BIO-RESPONSIVE ANTIBODY COMPLEXES FOR ENHANCED IMMUNOTHERAPY NORTH CAROLINA STATE UNIVERSITY 2022-06-02 US claimed
CN-114306281-A Visual heterozygous cell membrane nano-delivery system and preparation method and application thereof 中国医学科学院生物医学工程研究所 2022-04-12 CN claimed
CN-114081958-A Functionalized apoptotic body drug delivery system and preparation method and application thereof 中国医学科学院生物医学工程研究所 2022-02-25 CN claimed
EP-3934658-A1 BIO-RESPONSIVE ANTIBODY COMPLEXES FOR ENHANCED IMMUNOTHERAPY North Carolina State University (US) 2022-01-12 EP claimed
CN-113645980-A Bioresponse antibody complexes for enhanced immunotherapy 北卡罗莱纳州立大学 2021-11-12 CN claimed
WO-2020185677-A1 BIO-RESPONSIVE ANTIBODY COMPLEXES FOR ENHANCED IMMUNOTHERAPY NORTH CAROLINA STATE UNIVERSITY (US) 2020-09-17 WO claimed