SCHEMBL8725922

SCHEMBL8725922

CC(C)NC(C)C.CCOP

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.50
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10761663 0.79 TDP1 (0.47) TDP1
Ether SCHEMBL4867180 0.78 TDP1 (0.53) TDP1LMNA
SCHEMBL8442969 0.76 TDP1 (0.61) TDP1
SCHEMBL27286430 0.76 TDP1 (0.61) TDP1
SCHEMBL641005 0.75
Hydrochloric Acid SCHEMBL27576263 0.73 TDP1 (0.57) TDP1
SCHEMBL28021736 0.72 TDP1 (0.67) TDP1
SCHEMBL27075356 0.71
Hydrochloric Acid SCHEMBL27893792 0.71
SCHEMBL8165167 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0739351-A4 MONOMERIC DIOLS AND PHOSPHATE LINKED OLIGOMERS FORMED THEREFROM ISIS PHARMACEUTICALS INC (US) 1998-10-21 EP disclosed
EP-0739351-A1 MONOMERIC DIOLS AND PHOSPHATE LINKED OLIGOMERS FORMED THEREFROM ISIS PHARMACEUTICALS, INC. (US) 1996-10-30 EP disclosed
WO-1995018820-A1 MONOMERIC DIOLS AND PHOSPHATE LINKED OLIGOMERS FORMED THEREFROM ISIS PHARMACEUTICALS, INC. (US) 1995-07-13 WO disclosed