Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GGH | Q92820 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726793 | 1.00 | FOLH1 (0.35) | FOLH1RIMKLANAALAD2SLC6A2SLC6A4 | |
| SCHEMBL8726801 | 0.88 | — | — | |
| SCHEMBL910826 | 0.79 | FOLH1 (0.52) | FOLH1RIMKLANAALAD2SLC6A2SLC6A4 | |
| SCHEMBL910825 | 0.79 | FOLH1 (0.52) | FOLH1RIMKLANAALAD2SLC6A2SLC6A4 | |
| SCHEMBL910807 | 0.79 | FOLH1 (0.52) | FOLH1RIMKLANAALAD2SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL8726781 | 0.77 | FOLH1 (0.50) | FOLH1RIMKLANAALAD2SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL8726784 | 0.77 | FOLH1 (0.50) | FOLH1RIMKLANAALAD2SLC6A2SLC6A4 | |
| SCHEMBL27683390 | 0.77 | FOLH1 (0.50) | FOLH1RIMKLANAALAD2SLC6A2SLC6A4 | |
| SCHEMBL5141196 | 0.76 | TSHR (0.44) | FOLH1RIMKLANAALAD2SLC6A2SLC6A4 | |
| SCHEMBL27942121 | 0.76 | TSHR (0.44) | FOLH1RIMKLANAALAD2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770731-A | PROTECTING GROUPS, ANTIBODY DIRECTED ENZYME/PRODRUG THERAPY, ANTICARCINOGENIC AGENTS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1998-06-23 | — | — | US | disclosed |
| US-5728868-A | Prodrugs of protein tyrosine kinase inhibitors | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |