Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | AS3MT | Q9HBK9 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4309390 | 0.82 | MAOB (0.50) | MAOBMAPTL3MBTL1MAPK1TDP1 | |
| SCHEMBL11521229 | 0.80 | PTPN1 (0.52) | MAOBTSHRMAPTL3MBTL1MAPK1 | |
| SCHEMBL28326137 | 0.78 | MAOB (0.51) | MAOBMAPTL3MBTL1MAPK1TDP1 | |
| Fluoride SCHEMBL28325117 | 0.76 | MAOB (0.56) | MAOBTSHRMAPTL3MBTL1MAPK1 | |
| SCHEMBL27496007 | 0.74 | KDM4E (0.46) | TSHRIMPDH2GAAMEN1ALDH1A1 | |
| SCHEMBL6950623 | 0.73 | MAOB (0.54) | MAOBIMPDH2SMN1; SMN2GAAXDH | |
| SCHEMBL19828694 | 0.73 | PTPN1 (0.56) | MAOBTSHRMAPTL3MBTL1MAPK1 | |
| SCHEMBL8316680 | 0.73 | MAOB (0.55) | MAOBTSHRMAPTL3MBTL1MAPK1 | |
| SCHEMBL23887978 | 0.73 | MAOB (0.74) | MAOBMAPTL3MBTL1IMPDH2SMN1; SMN2 | |
| SCHEMBL627370 | 0.73 | MAOB (0.74) | MAOBMAPTL3MBTL1IMPDH2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873356-A1 | NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-28 | — | — | EP | disclosed |