Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8728106 | 1.00 | SPHK1 (0.43) | SPHK1SPHK2CYP2C9ESR2ALDH1A1 | |
| SCHEMBL8727632 | 0.91 | SPHK1 (0.45) | SPHK1SPHK2ALDH1A1 | |
| SCHEMBL8727636 | 0.91 | SPHK1 (0.45) | SPHK1SPHK2ALDH1A1 | |
| SCHEMBL8727072 | 0.87 | SPHK1 (0.43) | SPHK1SPHK2ALDH1A1 | |
| SCHEMBL8727066 | 0.87 | SPHK1 (0.43) | SPHK1SPHK2ALDH1A1 | |
| SCHEMBL8732252 | 0.86 | SPHK1 (0.41) | SPHK1SPHK2CYP2C9ESR2ALDH1A1 | |
| SCHEMBL8732256 | 0.86 | SPHK1 (0.41) | SPHK1SPHK2CYP2C9ESR2ALDH1A1 | |
| SCHEMBL8725401 | 0.86 | SPHK1 (0.48) | SPHK1SPHK2 | |
| SCHEMBL8725396 | 0.86 | SPHK1 (0.48) | SPHK1SPHK2 | |
| SCHEMBL8728046 | 0.85 | SPHK1 (0.46) | SPHK1SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882695-A1 | BENZYL ETHER DERIVATIVES, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY | CHISSO CORPORATION (JP) | 1998-12-09 | — | — | EP | disclosed |