Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | NPY5R | Q15761 | 12/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.53 |
| ▸ | NPY2R | P49146 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26707660 | 0.85 | GAA (0.74) | GAANPY5RALDH1A1KDM4EAOC3 | |
| SCHEMBL3447214 | 0.85 | GAA (0.74) | GAANPY5RALDH1A1KDM4EAOC3 | |
| SCHEMBL6908215 | 0.85 | GAA (0.74) | GAANPY5RALDH1A1KDM4EAOC3 | |
| SCHEMBL3447213 | 0.85 | GAA (0.74) | GAANPY5RALDH1A1KDM4EAOC3 | |
| SCHEMBL6223855 | 0.85 | GAA (0.74) | GAANPY5RALDH1A1KDM4EAOC3 | |
| SCHEMBL13893334 | 0.84 | GAA (0.72) | GAANPY5RALDH1A1KDM4EAOC3 | |
| SCHEMBL8561317 | 0.84 | GAA (1.00) | GAANPY5RALDH1A1KDM4EAOC3 | |
| SCHEMBL9907064 | 0.84 | GAA (0.72) | GAANPY5RALDH1A1KDM4EAOC3 | |
| SCHEMBL8285851 | 0.84 | GAA (1.00) | GAANPY5RALDH1A1KDM4EAOC3 | |
| SCHEMBL879389 | 0.84 | GAA (1.00) | GAANPY5RALDH1A1KDM4EAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751927-A4 | SYNTHESIS OF COMPOUNDS WITH PREDETERMINED CHIRALITY | CALIFORNIA INST OF TECHN (US) | 1998-07-29 | — | — | EP | disclosed |
| EP-0751927-A1 | SYNTHESIS OF COMPOUNDS WITH PREDETERMINED CHIRALITY | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1997-01-08 | — | — | EP | disclosed |
| US-5488131-A | Synthesis of compounds with predetermined chirality | CALIFORNIA INSTITUTE OF TECHNOLOGY | 1996-01-30 | — | — | US | disclosed |
| WO-1995025714-A1 | SYNTHESIS OF COMPOUNDS WITH PREDETERMINED CHIRALITY | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1995-09-28 | — | — | WO | disclosed |