Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Methoxycinnamic Acid SCHEMBL21195188 | 0.93 | TDP1 (0.55) | TDP1THRBATMTAS1R3TAS1R1 | |
| SCHEMBL14698300 | 0.92 | TDP1 (0.62) | TDP1THRBATMTAS1R3TAS1R1 | |
| SCHEMBL35995 | 0.92 | TDP1 (0.62) | TDP1THRBATMTAS1R3TAS1R1 | |
| SCHEMBL35994 | 0.92 | TDP1 (0.62) | TDP1THRBATMTAS1R3TAS1R1 | |
| 4-Methoxycinnamic Acid SCHEMBL19717781 | 0.91 | TDP1 (0.58) | TDP1THRBATMTAS1R3TAS1R1 | |
| SCHEMBL28036638 | 0.91 | TDP1 (0.61) | TDP1THRBATMTAS1R3TAS1R1 | |
| SCHEMBL28200368 | 0.90 | TDP1 (0.60) | TDP1THRBATMTAS1R3TAS1R1 | |
| SCHEMBL28313815 | 0.89 | TDP1 (0.58) | TDP1THRBATMTAS1R3TAS1R1 | |
| Fenipentol SCHEMBL29031308 | 0.89 | TDP1 (0.54) | TDP1THRBATMTAS1R3TAS1R1 | |
| SCHEMBL19137922 | 0.88 | CA12 (0.57) | TDP1MAOBCA12AKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827506-A | MIXTURE OF DIHYDROXYACETONE AND AN AMINO ACID FOR APPLICATION TO SKIN | SCHERING-PLOUGH HEALTHCARE PRODUCTS, INC. (US) | 1998-10-27 | — | — | US | disclosed |