SCHEMBL8729470

SCHEMBL8729470

Nc1cc(Oc2ccccc2O)c(N)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.51
KMT2A Q03164 7/20 0.51
MAPT P10636 6/20 0.51
MCL1 Q07820 5/20 0.51
MAPK1 P28482 4/20 0.51
THRB P10828 3/20 0.51
NPSR1 Q6W5P4 3/20 0.51
PKM P14618 2/20 0.51
KDM4E B2RXH2 2/20 0.51
GRK6 P43250 1/20 0.51
USP2 O75604 1/20 0.51
POLB P06746 4/20 0.50
TDP1 Q9NUW8 3/20 0.50
CSNK1A1 P48729 2/20 0.50
CSNK1D P48730 2/20 0.50
CSNK1G1 Q9HCP0 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
HPGD P15428 2/20 0.50
PABPC1 P11940 1/20 0.50
BLM P54132 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9161384 0.90 MEN1 (0.49) MEN1KMT2AMAPTMCL1MAPK1
SCHEMBL10810904 0.82 MAPK1 (0.48) MEN1KMT2AMAPTMCL1MAPK1
SCHEMBL8734315 0.82 ADORA2A (0.52) MEN1KMT2AMAPTMCL1MAPK1
SCHEMBL10817109 0.81 ADORA2A (0.55) MEN1KMT2AMAPTMCL1MAPK1
SCHEMBL92415 0.81 ADORA2A (0.66) MEN1KMT2AMAPTMCL1MAPK1
SCHEMBL8748104 0.80 ADORA2A (0.50) MEN1KMT2AMAPTMCL1MAPK1
SCHEMBL11117790 0.78 EGFR (0.42) MEN1KMT2AMAPTMCL1MAPK1
SCHEMBL10906450 0.78 KMT2A (0.44) MEN1KMT2AMAPTMCL1MAPK1
SCHEMBL8983801 0.78 MEN1 (0.63) MEN1KMT2AMAPTMCL1MAPK1
SCHEMBL9156103 0.78 MAPT (0.49) MEN1KMT2AMAPTMCL1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0739949-B1 Sublimation thermal-transfer printing MITSUI CHEMICALS INC (JP) 1998-09-16 EP disclosed
EP-0323744-B1 Transfer sheet ink and method for sublimation thermal-transfer printing MITSUI TOATSU CHEMICALS (JP) 1997-03-19 EP disclosed
EP-0739949-A1 Magenta dyestuff for sublimation thermal-transfer printing MITSUI TOATSU CHEMICALS, Inc. (JP) 1996-10-30 EP disclosed
US-5300475-A Anthraquinone dyes MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-04-05 US disclosed
US-5168093-A Colorfast anthraquinone dyes MITSUI TOATSU CHEMICALS INC. (JP) 1992-12-01 US disclosed
EP-0323744-A2 Transfer sheet ink and method for sublimation thermal-transfer printing MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-07-12 EP disclosed