SCHEMBL8729568

SCHEMBL8729568

C[Si](C)(O)O[Si](O)(O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL119554 0.82
SCHEMBL216545 0.75
SCHEMBL12894247 0.75
SCHEMBL401264 0.75
SCHEMBL16691833 0.75
SCHEMBL12665290 0.75
SCHEMBL133947 0.75
SCHEMBL16791000 0.75
SCHEMBL4326201 0.72
SCHEMBL677683 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0494842-B1 Rigid contact lenses with improved oxygen permeability CIBA GEIGY AG (CH) 1998-04-22 EP claimed
EP-0494842-A2 Rigid contact lenses with improved oxygen permeability CIBA-GEIGY AG (CH) 1992-07-15 EP claimed
US-11822182-B2 Wire grid polarizer with multi-layer silane conformal coating MOXTEK, INC. (US) 2023-11-21 US disclosed
US-20090081459-A1 ORGANIC FOAMING PLASTIC BODY HAVING EXCELLENT THERMAL RESISTANCE AND DURABILITY KYUNG-DONG CERATECH CO., LTD. (KR) 2009-03-26 US disclosed
EP-0494842-B1 Rigid contact lenses with improved oxygen permeability CIBA GEIGY AG (CH) 1998-04-22 EP disclosed
US-5194556-A Macromolecular monomer derived from polysiloxane copolymerized with fluoroacrylate CIBA-GEIGY CORPORATION (US) 1993-03-16 US disclosed
EP-0494842-A2 Rigid contact lenses with improved oxygen permeability CIBA-GEIGY AG (CH) 1992-07-15 EP disclosed
US-4923906-A Rigid, gas-permeable polysiloxane contact lenses CIBA-GEIGY CORPORATION (US) 1990-05-08 US disclosed