SCHEMBL872969

SCHEMBL872969

NC(=O)CC(Cl)C(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5315076 0.80
SCHEMBL5983734 0.80
SCHEMBL5983730 0.80
SCHEMBL28101648 0.75 CA1 (0.33)
SCHEMBL8090347 0.75
SCHEMBL7521024 0.73
SCHEMBL7860237 0.73
SCHEMBL332484 0.73
SCHEMBL7524232 0.73
SCHEMBL7514559 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 225 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021158891-A1 SALTS AND SOLID FORMS AND PROCESSES OF PREPARING A PI3K INHIBITOR INCYTE CORPORATION (US) 2021-08-12 WO claimed
CN-111333598-A Synthesis method of R-3-propyl-gamma-butyrolactone 武汉利昌医药科技有限公司 2020-06-26 CN claimed
WO-2020128469-A1 SYNTHESIS OF 8-CHLOROADENOSINE DERIVATIVES INCLUDING NUC-9701 NuCana plc (GB) 2020-06-25 WO claimed
CN-110129580-A A kind of method that soaking while grinding and its equipment strengthens the leaching of chalcopyrite normal pressure organic halogenation 东北大学 2019-08-16 CN claimed
CN-105503882-B The method for preparing S1P1 receptor modulators and its crystal form 艾尼纳制药公司 2019-07-05 CN claimed
CN-109516905-A The preparation method of inexpensive dihydro jasmone 盐城市春竹香料有限公司 2019-03-26 CN claimed
CN-108602765-A Method for producing 1, 2-benzenedimethanol compound SDS生物技术株式会社 2018-09-28 CN claimed
CN-108467766-A A kind of engine repair agent 温州巨耀汽车服务有限公司 2018-08-31 CN claimed
CN-108435132-A A kind of auxiliary agent improving fluid catalytic cracking product yield 广东石油化工学院 2018-08-24 CN claimed
CN-108290903-A New big ring sulphonyl diimine compounds 拜耳医药股份有限公司 2018-07-17 CN claimed
WO-2018104953-A1 IMPROVED PROCESS FOR THE PREPARATION OF 7-{4-[4-(2,3-DICHLOROPHENYL)-PIPERAZIN-1-YL]BUTOXY}-2OXO-3,4-DIHYDRO-2H-QUINOLIN-1-YL)METHYL DODECANOATE MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) 2018-06-14 WO claimed
CN-105593214-B Method for synthesizing N-benzyl-N-cyclopropyl-1H-pyrazole-4-formamide derivative 拜耳作物科学股份公司 2018-05-29 CN claimed
CN-106687462-A Processes of preparing a jak1 inhibitor and new forms thereto 因赛特公司 2017-05-17 CN claimed
CN-106467448-A For the alkene polymerization inhibitor in methanol-to-olefins device caustic wash tower 中国石油化工股份有限公司 2017-03-01 CN claimed
CN-106467447-A The method of olefinic polymerization in suppression methanol-to-olefins device caustic wash tower 中国石油化工股份有限公司 2017-03-01 CN claimed
WO-2014163933-A1 PROCESS FOR PREPARATION OF TRIARYL PESTICIDE INTERMEDIATE DOW AGROSCIENCES LLC (US) 2014-10-09 WO claimed
EP-1814857-A1 ISOTOPICALLY MARKED QUINOLINE DERIVATIVES AS ADENOSIN A3 RECEPTOR LIGANDS Sanofi-Aventis (FR) 2007-08-08 EP claimed
WO-2006083417-A2 PROCESSES OF MAKING SESQUITERPENOID TASHIRONIN, ITS ANALOGS AND THEIR USES THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2006-08-10 WO claimed
WO-2006051341-A1 ISOTOPICALLY MARKED QUINOLINE DERIVATIVES AS ADENOSIN A3 RECEPTOR LIGANDS SANOFI-AVENTIS (FR) 2006-05-18 WO claimed
CN-112300172-B Bruton tyrosine kinase inhibitors 比奥根MA公司 2024-01-16 CN disclosed
WO-2023205344-A1 SMALL MOLECULE MODULATORS OF HUMAN PREGNANE X RECEPTOR ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) 2023-10-26 WO disclosed
EP-4013495-A1 ARYLSULFONAMIDE DERIVATIVES AS MGLUR4 NEGATIVE ALLOSTERIC MODULATORS F. Hoffmann-La Roche AG (CH) 2022-06-22 EP disclosed
EP-3965760-A1 SYNTHESIS OF CRAC CHANNEL INHIBITORS Calcimedica, Inc. (US) 2022-03-16 EP disclosed
EP-3953331-A1 PYRAZOLESULFONAMIDES AS ANTITUMOR AGENTS Peloton Therapeutics, Inc. (US) 2022-02-16 EP disclosed
WO-2021158891-A1 SALTS AND SOLID FORMS AND PROCESSES OF PREPARING A PI3K INHIBITOR INCYTE CORPORATION (US) 2021-08-12 WO disclosed
EP-3484875-B1 PYRAZOLYLAMINOBENZIMIDAZOLE DERIVATIVES AS JAK INHIBITORS LILLY CO ELI (US) 2021-04-07 EP disclosed
WO-2021028512-A1 ARYLSULFONAMIDE DERIVATIVES AS MGLUR4 NEGATIVE ALLOSTERIC MODULATORS F. HOFFMANN-LA ROCHE AG (CH) 2021-02-18 WO disclosed
WO-2020227592-A1 THIOSEMICARBAZATES AND USES THEREOF THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2020-11-12 WO disclosed
WO-2020210139-A1 PYRAZOLESULFONAMIDES AS ANTITUMOR AGENTS PELOTON THERAPEUTICS, INC. (US) 2020-10-15 WO disclosed
WO-2020157710-A1 4-SUBSTITUTED ISOXAZOLE/ISOXAZOLINE (HETERO) ARYLAMIDINE COMPOUNDS, PREPARATION AND USE THEREOF PI INDUSTRIES LTD. (IN) 2020-08-06 WO disclosed
CN-111333598-A Synthesis method of R-3-propyl-gamma-butyrolactone 武汉利昌医药科技有限公司 2020-06-26 CN disclosed
EP-3298001-B1 DGAT2 INHIBITORS LILLY CO ELI (US) 2020-05-13 EP disclosed
CN-110506043-A COMPOUNDS USEFUL AS RET INHIBITORS CANCER RES TECH LIMITED 2019-11-26 CN disclosed
CN-107207432-B Pyrroles's sulphonyl analog derivative, preparation method and its application in medicine 江苏柯菲平医药股份有限公司 2019-09-17 CN disclosed
CN-110230071-A A method of β-halo carbonyl compounds are prepared using high-salt wastewater 上海交通大学 2019-09-13 CN disclosed
CN-110129580-A A kind of method that soaking while grinding and its equipment strengthens the leaching of chalcopyrite normal pressure organic halogenation 东北大学 2019-08-16 CN disclosed
CN-106467448-B For the alkene polymerization inhibitor in methanol-to-olefins device caustic wash tower 中国石油化工股份有限公司 2019-08-06 CN disclosed
EP-3515903-A1 PREPARATION AND USES OF PYRIMIDINONE DERIVATIVES Cancer Research Technology Limited (GB) 2019-07-31 EP disclosed
CN-110072847-A 1,3- dipolar compound with conjugation carbon-to-carbon double bond 米其林集团总公司 2019-07-30 CN disclosed
US-10344018-B2 Pyrazolylaminobenzimidazole derivatives as JAK inhibitors ELI LILLY AND COMPANY (US) 2019-07-09 US disclosed
CN-109983001-A 2, 5-disubstituted 3-methylpyrazine and 2,5, 6-trisubstituted 3-methylpyrazine as allosteric SHP2 inhibitors 锐新医药公司 2019-07-05 CN disclosed
CN-105503882-B The method for preparing S1P1 receptor modulators and its crystal form 艾尼纳制药公司 2019-07-05 CN disclosed
CN-106990079-B A kind of surface multifunctional coating and the preparation method and application thereof 中国科学院化学研究所 2019-06-25 CN disclosed
US-10323019-B2 Pyrazolylaminobenzimidazole derivatives as JAK inhibitors ELI LILLY AND COMPANY (US) 2019-06-18 US disclosed
CN-109890208-A FUNGICIDAL COMPOSITIONS 先正达参股股份有限公司 2019-06-14 CN disclosed
US-20190177300-A1 PYRAZOLYLAMINOBENZIMIDAZOLE DERIVATIVES AS JAK INHIBITORS LILLY CO ELI (US) 2019-06-13 US disclosed
CN-109803962-A Modulators of cystic fibrosis transmembrane conductance regulator proteins, pharmaceutical compositions, methods of treatment, and methods for making the modulators 弗特克斯药品有限公司 2019-05-24 CN disclosed
EP-3484875-A1 PYRAZOLYLAMINOBENZIMIDAZOLE DERIVATIVES AS JAK INHIBITORS Eli Lilly and Company (US) 2019-05-22 EP disclosed
CN-105176641-B A kind of lubricant oil composite and preparation method thereof of tractor three 中国石油化工股份有限公司 2019-04-16 CN disclosed
CN-109563062-A The manufacture of sulfonyl azide acid anhydrides 陶氏环球技术有限责任公司 2019-04-02 CN disclosed
CN-107428935-B Diamine compound, heat-resistant resin or heat-resistant resin precursor using it 东丽株式会社 2019-04-02 CN disclosed
CN-109516905-A The preparation method of inexpensive dihydro jasmone 盐城市春竹香料有限公司 2019-03-26 CN disclosed
CN-106414442-B 1H- pyrrolo- [2,3-c] pyridine -7 (6H) -one and pyrazolo [3,4-c] pyridine -7 (6H) -one as BET protein inhibitor 因赛特公司 2019-03-15 CN disclosed
CN-103819467-B The preparation method and its usage of quinazoline derivant 中国科学院福建物质结构研究所 2019-03-08 CN disclosed
CN-109414680-A Functionalized chromatography media comprising polymeric nanofibers and methods of making the same 纯化迪发有限公司 2019-03-01 CN disclosed
WO-2018234353-A1 NOVEL SUBSTITUTED INDOLE AND INDAZOLE COMPOUNDS AS PHOSPHODIESTERASE INHIBITORS Grünenthal GmbH (DE) 2018-12-27 WO disclosed
CN-109071533-A Halogenated allylamine indoles and 7-azaindole derivatives inhibitor of lysyloxidase and application thereof 法玛西斯有限公司 2018-12-21 CN disclosed
CN-109071504-A Inhibitors of receptor interacting protein kinase 1 戴纳立制药公司 2018-12-21 CN disclosed
CN-105705510-B HCV polymerase inhibitors 美迪维尔公司 2018-11-30 CN disclosed
CN-108884035-A Indolo-substituted piperidines as estrogen receptor degraders 罗欣生物科技(上海)有限公司 2018-11-23 CN disclosed
US-20180325873-A1 PYRAZOLYLAMINOBENZIMIDAZOLE DERIVATIVES AS JAK INHIBITORS ELI LILLY AND COMPANY 2018-11-15 US disclosed
CN-108699028-A It is substituted 4- phenylpyridine compounds as non-systemic TGR5 agonists 阿德利克斯公司 2018-10-23 CN disclosed
CN-105451558-B Pyrazolyl pyrrolinone and its purposes as herbicide 先正达参股股份有限公司 2018-10-23 CN disclosed
CN-108676047-A Hcv polymerase inhibitors 美迪维尔公司 2018-10-19 CN disclosed
CN-108602765-A Method for producing 1, 2-benzenedimethanol compound SDS生物技术株式会社 2018-09-28 CN disclosed
CN-103601762-B Ferrocene derivatives, preparation method and its usage 中国科学院福建物质结构研究所 2018-09-28 CN disclosed
CN-108558973-A Hcv polymerase inhibitors 美迪维尔公司 2018-09-21 CN disclosed
WO-2018167801-A1 NOVEL TRICYCLIC COMPOUNDS, PROCESS FOR PREPARATION AND USE THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2018-09-20 WO disclosed
CN-108495898-A Double imide with rigidity 2,2 '-biphenylyloxies bridge joint 巴斯夫欧洲公司 2018-09-04 CN disclosed
CN-108473469-A Substituted 3-azabicyclo [3.1.0] hexanes as ketohexokinase inhibitors 辉瑞公司 2018-08-31 CN disclosed
CN-108435132-A A kind of auxiliary agent improving fluid catalytic cracking product yield 广东石油化工学院 2018-08-24 CN disclosed
EP-3362423-A1 DEUTERATED CHLOROKYNURENINES FOR THE TREATMENT OF NEUROPSYCHIATRIC DISORDERS Auspex Pharmaceuticals, Inc. (US) 2018-08-22 EP disclosed
US-10053429-B2 DGAT2 inhibitors ELI LILLY AND COMPANY (US) 2018-08-21 US disclosed
CN-108430986-A fused bicyclic heterocyclic derivatives as pest control agents 拜耳作物科学股份公司 2018-08-21 CN disclosed
CN-108290838-A Biaryl derivatives and drugs containing the same 科研制药株式会社 2018-07-17 CN disclosed
CN-108290903-A New big ring sulphonyl diimine compounds 拜耳医药股份有限公司 2018-07-17 CN disclosed
EP-3074381-B1 NOVEL DGAT2 INHIBITORS LILLY CO ELI (US) 2018-07-04 EP disclosed
CN-108191870-A For benzimidazole simultaneously [1,2-A] benzimidizole derivatives of electronic application UDC 爱尔兰有限责任公司 2018-06-22 CN disclosed
CN-108191719-A A kind of chalcone analog, preparation method and its medical usage of the substitution of class containing sulfone 中国药科大学 2018-06-22 CN disclosed
US-20180162825-A1 NOVEL DGAT2 INHIBITORS ELI LILY AND COMPANY (US) 2018-06-14 US disclosed
CN-108102774-A A kind of lubricating oil and its application 金雪驰科技(马鞍山)有限公司 2018-06-01 CN disclosed
CN-104870430-B Herbicidally active cyclic dione compounds substituted by phenyl groups having alkynyl-containing substituents or derivatives thereof 先正达有限公司 2018-05-29 CN disclosed
CN-105593214-B Method for synthesizing N-benzyl-N-cyclopropyl-1H-pyrazole-4-formamide derivative 拜耳作物科学股份公司 2018-05-29 CN disclosed
CN-108003991-A A kind of plant based lubricating oil and its application 金雪驰科技(马鞍山)有限公司 2018-05-08 CN disclosed
CN-107922380-A Microbicidal heterobicyclic derivatives 先正达参股股份有限公司 2018-04-17 CN disclosed
CN-107922408-A Microbicidal heterobicyclic derivatives 先正达参股股份有限公司 2018-04-17 CN disclosed
WO-2018055402-A1 PREPARATION AND USES OF PYRIMIDINONE DERIVATIVES CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2018-03-29 WO disclosed
CN-107848988-A Alkenyl substituted 2, 5-piperazinediones and their use in compositions for delivering an agent to a subject or cell 麻省理工学院 2018-03-27 CN disclosed
CN-107849022-A SUBSTITUTED QUINAZOLINE COMPOUNDS AND METHODS OF USE THEREOF 亚瑞克西斯制药公司 2018-03-27 CN disclosed
CN-104507945-B Pyrrolo- [2,3 B] pyrazine as SYK inhibitor 霍夫曼-拉罗奇有限公司 2018-03-23 CN disclosed
CN-107820497-A Imidazoles pyrazines derivatives for electronic installation 陶氏环球技术有限责任公司 2018-03-20 CN disclosed
CN-105324372-B 1-sulfonylpiperidine derivatives as prokineticin receptor modulators 武田药品工业株式会社 2018-03-06 CN disclosed
CN-105683188-B The ring pyridinyl derivatives of condensed ring two as FGFR4 inhibitor 诺华股份有限公司 2018-02-09 CN disclosed
CN-107635975-A NOVEL DGAT2 INHIBITORS 伊莱利利公司 2018-01-26 CN disclosed
CN-104395316-B Benzimidazo [1,2-A ] benzimidazole derivatives for electronic applications UDC 爱尔兰有限责任公司 2018-01-19 CN disclosed
CN-105820128-B A kind of preparation method of cyproconazole 江西华士药业有限公司 2018-01-19 CN disclosed
CN-105339347-B The ring dione compounds and its derivative of (alkynyl phenyl) substitution of activity of weeding 先正达有限公司 2018-01-19 CN disclosed
WO-2018013486-A1 PYRAZOLYLAMINOBENZIMIDAZOLE DERIVATIVES AS JAK INHIBITORS ELI LILLY AND COMPANY (US) 2018-01-18 WO disclosed
CN-107531739-A Nucleotide derivative as the HCV inhibitor for treating hepatitis C 美迪维尔公司 2018-01-02 CN disclosed
EP-3259253-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME The University of Queensland (AU) 2017-12-27 EP disclosed
CN-103946220-B Inhibitors of baculovirus containing fragment {2- [4- (biphenyl-4-yl) -1H-imidazol-2-yl ] pyrrolidine-1-carbonylmethyl } amine 施万生物制药研发IP有限责任公司 2017-12-22 CN disclosed
CN-102977029-B As 5 HT2ASerotonin receptor modulator is applied to treat 3 phenylpyrazole derivatives of relative illness 艾尼纳制药公司 2017-12-19 CN disclosed
CN-107428935-A Diamine compound, heat-resistant resin or heat-resistant resin precursor using it 东丽株式会社 2017-12-01 CN disclosed
CN-107353289-A Benzimidazole for electronic application simultaneously [1,2 A] benzimidizole derivatives UDC 爱尔兰有限责任公司 2017-11-17 CN disclosed
EP-3240788-A1 PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS Syngenta Participations AG (CH) 2017-11-08 EP disclosed
CN-107207432-A Pyrroles's sulphonyl analog derivative, its preparation method and its in application pharmaceutically 江苏柯菲平医药股份有限公司 2017-09-26 CN disclosed
CN-107207872-A Phthalein green grass or young crops pigment, coloured composition and colored filter 东洋油墨SC控股株式会社 2017-09-26 CN disclosed
CN-105377837-B N (heteroaryl) sulfamide derivative as S100 inhibitor 活跃生物技术有限公司 2017-08-04 CN disclosed
CN-107011401-A Deoxycholic acid compound and its purification process 凯瑟拉生物制药有限公司 2017-08-04 CN disclosed
CN-102119143-B Amide derivative, pest control agent containing the same, and method of using the pest control agent 三井化学AGRO株式会社 2017-07-21 CN disclosed
CN-105061313-B Androgen receptor modulating compounds 奥赖恩公司 2017-07-18 CN disclosed
CN-106955287-A Composition, purposes and its purification process of deoxycholic acid 凯瑟拉生物制药有限公司 2017-07-18 CN disclosed
EP-3169680-A1 NOVEL 2,5-SUBSTITUTED PYRIMIDINES AS PDE INHIBITORS Grünenthal GmbH (DE) 2017-05-24 EP disclosed
CN-106687462-A Processes of preparing a jak1 inhibitor and new forms thereto 因赛特公司 2017-05-17 CN disclosed
CN-104379576-B Substituted pyrrolidines as factor XIA inhibitors for the treatment of thromboembolic disorders 小野药品工业株式会社 2017-05-10 CN disclosed
WO-2017065899-A1 DEUTERATED CHLOROKYNURENINES FOR THE TREATMENT OF NEUROPSYCHIATRIC DISORDERS AUSPEX PHARMACEUTICALS, INC. (US) 2017-04-20 WO disclosed
CN-104011042-B Insecticidal triazinone derivatives 先正达参股股份有限公司 2017-03-29 CN disclosed
CN-104854087-B Indole carboxamide derivatives as P2X receptor antagonists 埃科特莱茵药品有限公司 2017-03-22 CN disclosed
CN-106536506-A Benzimidazole derivatives as erbb tyrosine kinase inhibitors for the treatment of cancer 卡佩拉医疗公司 2017-03-22 CN disclosed
CN-106488910-A Inhibitors of kras g12c 亚瑞克西斯制药公司 2017-03-08 CN disclosed
CN-106488916-A The new 2,5 substituted miazines as PDE inhibitor 格吕伦塔尔有限公司 2017-03-08 CN disclosed
CN-106467448-A For the alkene polymerization inhibitor in methanol-to-olefins device caustic wash tower 中国石油化工股份有限公司 2017-03-01 CN disclosed
CN-106467447-A The method of olefinic polymerization in suppression methanol-to-olefins device caustic wash tower 中国石油化工股份有限公司 2017-03-01 CN disclosed
CN-103864804-B Synthetic method for pranoprofen 天津金耀集团有限公司 2017-02-22 CN disclosed
CN-106459088-A 2-amino-6-methyl-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8h)-yl-1,3-thiazol-4-yl amides 辉瑞公司 2017-02-22 CN disclosed
CN-106414442-A 1H-PYRROLO[2,3-c]PYRIDIN-7(6H)-ONES AND PYRAZOLO[3,4-c]PYRIDIN-7(6H)-ONES AS INHIBITORS OF BET PROTEINS 因赛特公司 2017-02-15 CN disclosed
WO-2016199020-A1 PROCESS FOR PREPARATION OF CERITINIB DR. REDDY'S LABORATORIES LIMITED (IN) 2016-12-15 WO disclosed
EP-3074381-A1 NOVEL DGAT2 INHIBITORS Eli Lilly and Company (US) 2016-10-05 EP disclosed
WO-2016131098-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME THE UNIVERSITY OF QUEENSLAND (AU) 2016-08-25 WO disclosed
EP-3044226-A1 ARYL ETHER-BASE KINASE INHIBITORS Bristol-Myers Squibb Company (US) 2016-07-20 EP disclosed
WO-2016107742-A1 PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2016-07-07 WO disclosed
CN-103797024-B Hepatitis c virus inhibitors BRISTOL-MYERS SQUIBB CO. (US) 2016-06-01 CN disclosed
WO-2016046782-A1 IMIDAZOLE BIARYL COMPOUNDS AS S-NITROSOGLUTATHIONE REDUCTASE INHIBITORS GLENMARK PHARMACEUTICALS S.A. (CH) 2016-03-31 WO disclosed
WO-2016008592-A1 NOVEL 2,5-SUBSTITUTED PYRIMIDINES AS PDE INHIBITORS Grünenthal GmbH (DE) 2016-01-21 WO disclosed
CN-105176641-A Tractor three-purpose lubricating oil composition and preparation method of tractor three-purpose lubricating oil composition CHINA PETROLEUM & CHEMICAL 2015-12-23 CN disclosed
WO-2015191677-A1 BICYCLIC HETEROARYLAMINOALKYL PHENYL DERIVATIVES AS PI3K INHIBITORS INCYTE CORPORATION (US) 2015-12-17 WO disclosed
EP-2951170-A2 FLAP MODULATORS Janssen Pharmaceutica, N.V. (BE) 2015-12-09 EP disclosed
US-9073901-B2 DGAT2 inhibitors ELI LILLY AND COMPANY (US) 2015-07-07 US disclosed
WO-2015077299-A1 NOVEL DGAT2 INHIBITORS ELI LILLY AND COMPANY (US) 2015-05-28 WO disclosed
US-20150148358-A1 NOVEL DGAT2 INHIBITORS ELI LILLY AND COMPANY (US) 2015-05-28 US disclosed
EP-2855452-A1 SUBSTITUTED PYRROLIDINES AS FACTOR XIA INHIBITORS FOR THE TREATMENT THROMBOEMBOLIC DISEASES ONO Pharmaceutical Co., Ltd. (JP) 2015-04-08 EP disclosed
WO-2015038112-A1 ARYL ETHER-BASE KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2015-03-19 WO disclosed
EP-2836487-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF Infinity Pharmaceuticals, Inc. (US) 2015-02-18 EP disclosed
EP-2822952-A1 ARYL ETHER-BASE KINASE INHIBITORS Bristol-Myers Squibb Company (US) 2015-01-14 EP disclosed
WO-2014121055-A2 FLAP MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2014-08-07 WO disclosed
EP-2697283-A1 SEMICONDUCTING POLYMERS University of Chicago (US) 2014-02-19 EP disclosed
WO-2014016847-A1 A PROCESS FOR THE PREPARATION OF CINACALCET HYDROCHLORIDE AND ITS INTERMEDIATE TYCHE INDUSTRIES LIMITED (IN) 2014-01-30 WO disclosed
EP-2673285-A1 KETOLIDE COMPOUNDS Wockhardt Limited (IN) 2013-12-18 EP disclosed
WO-2013174937-A1 SUBSTITUTED PYRROLIDINES AS FACTOR XIA INHIBITORS FOR THE TREATMENT THROMBOEMBOLIC DISEASES ONO PHARMACEUTICAL CO., LTD (JP) 2013-11-28 WO disclosed
WO-2013154878-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF INFINITY PHARMACEUTICALS, INC. (US) 2013-10-17 WO disclosed
WO-2013134036-A1 ARYL ETHER-BASE KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2013-09-12 WO disclosed
CN-102803218-A 4 -aminopicolinates And Their Use As Herbicides SYNGENTA LTD 2012-11-28 CN disclosed
EP-2513091-A1 HEPATITIS C VIRUS INHIBITORS Bristol-Myers Squibb Company (US) 2012-10-24 EP disclosed
WO-2012142469-A1 SEMICONDUCTING POLYMERS UNIVERSITY OF CHICAGO (US) 2012-10-18 WO disclosed
EP-2493866-A1 TRICYCLIC HETEROCYCLIC COMPOUNDS Bristol-Myers Squibb Company (US) 2012-09-05 EP disclosed
WO-2012076989-A1 KETOLIDE COMPOUNDS WOCKHARDT LIMITED (IN) 2012-06-14 WO disclosed
WO-2012038966-A1 PROCESS FOR THE PREPARATION OF DONEPEZIL INTERMEDIATE TYCHE INDUSTRIES LTD. (IN) 2012-03-29 WO disclosed
WO-2011075630-A1 SUBSTITUTED FUSED ARYL AND HETEROARYL DERIVATIVES AS PI3K INHIBITORS INCYTE CORPORATION (US) 2011-06-23 WO disclosed
WO-2011075439-A1 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2011-06-23 WO disclosed
WO-2011059784-A1 TRICYCLIC HETEROCYCLIC COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2011-05-19 WO disclosed
WO-2011038313-A2 SELECTIVE OXIDATION OF C-H BONDS OF MODIFIED SUBSTRATES BY P450 MONOOXYGENASE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2011-03-31 WO disclosed
WO-2010141592-A2 CHEMICAL FRAGMENT SCREENING AND ASSEMBLY UTILIZING COMMON CHEMISTRY FOR NMR PROBE INTRODUCTION AND FRAGMENT LINKAGE MARQUETTE UNIVERSITY (US) 2010-12-09 WO disclosed
EP-2225203-A1 DEHYDROHALOGENATION PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL IN PROVIDING 6,6-DIMETHYL-3-AZABICYCLO-[3.1.0]-HEXANE COMPOUNDS Schering Corporation (US) 2010-09-08 EP disclosed
CN-101743230-A Arylpyrrol-2-yl cyanoethylamino compounds, process for their preparation and their use AVENTIS AGRICULTURE 2010-06-16 CN disclosed
WO-2010024980-A1 4'-AMINO CYCLIC COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY MEMORY PHARMACEUTICALS CORPORATION (US) 2010-03-04 WO disclosed
WO-2010021797-A1 CONDENSED HETEROCYCLIC COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY MEMORY PHARMACEUTICALS CORPORATION (US) 2010-02-25 WO disclosed
WO-2010011546-A2 ACYCLIC COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY MEMORY PHARMACEUTICALS CORPORATION (US) 2010-01-28 WO disclosed
WO-2010008832-A1 PYRROLO-PYRIDINE-3-YL-PIPERAZINE DERIVATIVES HAVING 5-HT6 RECEPTOR AFFINITY MEMORY PHARMACEUTICALS CORPORATION (US) 2010-01-21 WO disclosed
WO-2010002802-A1 PYRROLIDINE-SUBSTITUTED AZAINDOLE COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY MEMORY PHARMACEUTICALS CORPORATION (US) 2010-01-07 WO disclosed
EP-2125675-A1 METHODS FOR GASSING EXPLOSIVES ESPECIALLY AT LOW TEMPERATURES Newcastle Innovation Limited (AU) 2009-12-02 EP disclosed
CN-101568505-A For treating NO-containing substancesxOr an ethylene oxide stream of an organic nitrogen compound DOW TECHNOLOGY INVESTMENTS LLC (US) 2009-10-28 CN disclosed
EP-2097362-A1 PROCESS FOR REDUCING SIDE-REACTIONS DURING ALKYLENE GLYCOL AND POLY-ALKYLENE GLYCOL MANUFACTURING Dow Technology Investments LLC (US) 2009-09-09 EP disclosed
CN-101528033-A Cropping systems for managing weeds MONSANTO TECHNOLOGY LLC (US) 2009-09-09 CN disclosed
CN-101511840-A Phosphoinositide 3-kinase inhibitor compounds and methods of use thereof GENENTECH INC (US) 2009-08-19 CN disclosed
WO-2009073380-A1 DEHYDROHALOGENATION PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL IN PROVIDING 6,6-DIMETHYL-3-AZABICYCLO-[3.1.0]-HEXANE COMPOUNDS SCHERING CORPORATION (US) 2009-06-11 WO disclosed
EP-2029579-A2 CYCLOHEXYLPYRAZOLE-LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 ELI LILLY AND COMPANY (US) 2009-03-04 EP disclosed
EP-2021338-A1 CYCLOALKYLAMINO ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF Pfizer Products Inc. (US) 2009-02-11 EP disclosed
WO-2008085268-A1 PROCESS FOR PROCESSING ETHYLENE OXIDE STREAMS CONTAINING NOX OR ORGANIC NITROGEN COMPOUNDS DOW TECHNOLOGY INVESTMENTS LLC (US) 2008-07-17 WO disclosed
WO-2008085267-A1 PROCESS FOR REDUCING SIDE-REACTIONS DURING ALKYLENE GLYCOL AND POLY-ALKYLENE GLYCOL MANUFACTURING DOW TECHNOLOGY INVESTMENTS LLC (US) 2008-07-17 WO disclosed
WO-2008083436-A1 METHODS FOR GASSING EXPLOSIVES ESPECIALLY AT LOW TEMPERATURES NEWCASTLE INNOVATION LIMITED (AU) 2008-07-17 WO disclosed
EP-1863494-A1 USE OF VITAMIN D COMPOUNDS TO TREAT ENDOMETRIOSIS Bioxell S.p.a. (IT) 2007-12-12 EP disclosed
EP-1858902-A1 BICYCLIC HETEROAROMATIC DERIVATIVES USEFUL AS ANTICANCER AGENTS Pfizer Products Incorporated (US) 2007-11-28 EP disclosed
WO-2007132307-A1 CYCLOALKYLAMINO ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF PFIZER PRODUCTS INC. (US) 2007-11-22 WO disclosed
WO-2007124254-A2 CYCLOHEXYLPYRAZOLE-LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 ELI LILLY AND COMPANY (US) 2007-11-01 WO disclosed
EP-1778634-A1 ISOINDOLONE COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS AstraZeneca AB (SE) 2007-05-02 EP disclosed
WO-2006100285-A1 USE OF VITAMIN D COMPOUNDS TO TREAT ENDOMETRIOSIS BIOXELL SPA (IT) 2006-09-28 WO disclosed
WO-2006090261-A1 BICYCLIC HETEROAROMATIC DERIVATIVES USEFUL AS ANTICANCER AGENTS PFIZER PRODUCTS INC. (US) 2006-08-31 WO disclosed
WO-2006083417-A2 PROCESSES OF MAKING SESQUITERPENOID TASHIRONIN, ITS ANALOGS AND THEIR USES THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2006-08-10 WO disclosed
WO-2006069155-A2 INHIBITORS OF PROTEIN ARGININE METHYL TRANSFERASES BRISTOL-MYERS SQUIBB COMPANY (US) 2006-06-29 WO disclosed
WO-2006035075-A1 USE OF VITAMIN D COMPOUNDS FOR THE PREVENTION OR TREATMENT OF CHRONIC PROSTATITIS BIOXELL SPA (IT) 2006-04-06 WO disclosed
WO-2006020879-A1 ISOINDOLONE COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS ASTRAZENECA AB (SE) 2006-02-23 WO disclosed
EP-1567527-A1 CONDENSED PYRAZOLO DERIVATIVES ELI LILLY AND COMPANY (US) 2005-08-31 EP disclosed
EP-1539795-A1 CRYSTALLINE 17BETA-HYDROXY-7ALPHA-(5'-METHYL-2'-FURYL)-PREGNA-4,9(11)-DIEN-3-ONE-21-CARBOXYLIC ACID, GAMMA-LACTONE Pharmacia & Upjohn Company LLC (US) 2005-06-15 EP disclosed
EP-1539662-A1 CANNABINOID RECEPTOR LIGANDS SCHERING CORPORATION (US) 2005-06-15 EP disclosed
EP-1487859-A2 PROCESS TO PREPARE EPLERENONE PHARMACIA &amp; UPJOHN COMPANY (US) 2004-12-22 EP disclosed
WO-2004050659-A1 NOVEL COMPOUNDS AS PHARMACEUTICAL AGENTS ELI LILLY AND COMPANY (US) 2004-06-17 WO disclosed
WO-2004037844-A1 CRYSTALLINE 17BETA-HYDROXY-7ALPHA- (5'-METHYL-2'-FURYL)-PREGNA-4,9(11)-DIEN-3-ONE-21-CARBOXYLIC ACID, GAMMA-LACTONE PHARMACIA & UPJOHN COMPANY (US) 2004-05-06 WO disclosed
EP-1401820-A1 5-HT RECEPTOR LIGANDS AND USES THEREOF Pfizer Products Inc. (US) 2004-03-31 EP disclosed
WO-2004014825-A1 CANNABINOID RECEPTOR LIGANDS SCHERING CORPORATION (US) 2004-02-19 WO disclosed
EP-1373194-A1 BENZAMIDE INHIBITORS OF FACTOR Xa Millennium Pharmaceuticals, Inc. (US) 2004-01-02 EP disclosed
EP-1368308-A1 CANNABINOID RECEPTOR LIGANDS Schering Corporation (US) 2003-12-10 EP disclosed
WO-2003082895-A2 PROCESS TO PREPARE EPLERENONE PHARMACIA & UPJOHN COMPANY (US) 2003-10-09 WO disclosed
WO-2002062750-A9 CANNABINOID RECEPTOR LIGANDS SCHERING CORP (US) 2003-09-18 WO disclosed
WO-2003000666-A1 5-HT RECEPTOR LIGANDS AND USES THEREOF PFIZER PRODUCTS INC. (US) 2003-01-03 WO disclosed
WO-2002079145-A1 BENZAMIDE INHIBITORS OF FACTOR Xa MILLENNIUM PHARMACEUTICALS, INC. (US) 2002-10-10 WO disclosed
WO-2002062750-A1 CANNABINOID RECEPTOR LIGANDS SCHERING CORPORATION (US) 2002-08-15 WO disclosed
EP-1076558-A1 2-PHENYL-1-[-(2-AMINOETHOXY)-BENZYL -INDOLE IN COMBINATION WITH ESTROGENS AMERICAN HOME PRODUCTS CORPORATION (US) 2001-02-21 EP disclosed
EP-1056719-A2 INHIBITORS OF PHOSPHOLIPASE ENZYMES GENETICS INSTITUTE, INC. (US) 2000-12-06 EP disclosed
EP-0973749-A1 4-AMINOALKOXY-1H-BENZIMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINE AUTORECEPTOR (D2) AGONISTS AMERICAN HOME PRODUCTS CORPORATION (US) 2000-01-26 EP disclosed
EP-0964854-A1 4-AMINOALKOXY-1,3-DIHYDROBENZOIMIDAZOL-2-THIONES DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINE AUTORECEPTOR (D2) AGONISTS AMERICAN HOME PRODUCTS CORPORATION (US) 1999-12-22 EP disclosed
EP-0964853-A1 4-AMINOALKOXY-1,3-DIHYDROBENZOIMIDAZOL-2-ONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINE AUTORECEPTOR (D2) AGONISTS AMERICAN HOME PRODUCTS CORPORATION (US) 1999-12-22 EP disclosed
WO-1999059581-A1 2-PHENYL-1-[4-(2-AMINOETHOXY)-BENZYL]-INDOLE IN COMBINATION WITH ESTROGENS AMERICAN HOME PRODUCTS CORPORATION (US) 1999-11-25 WO disclosed
EP-0942912-A1 ANTIBACTERIAL AGENTS WARNER-LAMBERT COMPANY (US) 1999-09-22 EP disclosed
WO-1999043651-A2 INHIBITORS OF PHOSPHOLIPASE ENZYMES GENETICS INSTITUTE, INC. (US) 1999-09-02 WO disclosed
WO-1998035946-A1 4-AMINOALKOXY-1,3-DIHYDROBENZOIMIDAZOL-2-ONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINE AUTORECEPTOR (D2) AGONISTS AMERICAN HOME PRODUCTS CORPORATION (US) 1998-08-20 WO disclosed
WO-1998035947-A1 4-AMINOALKOXY-1,3-DIHYDROBENZOIMIDAZOL-2-THIONES DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINE AUTORECEPTOR (D2) AGONISTS AMERICAN HOME PRODUCTS CORPORATION (US) 1998-08-20 WO disclosed
WO-1998035945-A1 4-AMINOALKOXY-1H-BENZIMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINE AUTORECEPTOR (D2) AGONISTS AMERICAN HOME PRODUCTS CORPORATION (US) 1998-08-20 WO disclosed
WO-1998025932-A1 ANTIBACTERIAL AGENTS WARNER-LAMBERT COMPANY (US) 1998-06-18 WO disclosed
EP-0691966-A1 QUINOLINES AS TYPE IV PHOSPHODIESTERASE INHIBITORS SYNTEX (U.S.A.) INC. (US) 1996-01-17 EP disclosed
WO-1995029904-A1 SUBSTITUTED THIAZOLE SULFONAMIDES AS ANTIGLAUCOMA AGENTS ALLERGAN (US) 1995-11-09 WO disclosed
EP-0673360-A1 AMINOMETHYLINDANS, -BENZOFURANES AND -BENZOTHIOPHENES H. LUNDBECK A/S (DK) 1995-09-27 EP disclosed
WO-1994013620-A1 AMINOMETHYLINDANS, -BENZOFURANES AND -BENZOTHIOPHENES H. LUNDBECK A/S (DK) 1994-06-23 WO disclosed
US-5077394-A Tetraphenyl-type with electronegative substituents; oxidation catalysts for alkanes and alkenes SANDOZ LTD. (CH) 1991-12-31 US disclosed
US-4892941-A OXIDATION CATALYSTS, LIGNIN, HYDROXYLATION, EPOXIDATION CLARIANT FINANCE (BVI) LIMITED (VG) 1990-01-09 US disclosed
EP-0124461-B1 METHOD AND COMPOSITION FOR CLEANING AND DECONTAMINATING CONTACT LENSES Laboratoires P.O.S. Société Anonyme dite: (FR) 1987-03-18 EP disclosed
EP-0124461-B1 METHOD AND COMPOSITION FOR CLEANING AND DECONTAMINATING CONTACT LENSES Laboratoires P.O.S. Société Anonyme dite: (FR) 1987-03-18 EP disclosed