⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2409250 | 0.84 | — | — | |
| SCHEMBL6835983 | 0.79 | — | — | |
| SCHEMBL1035580 | 0.77 | — | — | |
| SCHEMBL11039853 | 0.72 | — | — | |
| SCHEMBL128394 | 0.72 | — | — | |
| SCHEMBL129840 | 0.70 | — | — | |
| SCHEMBL8017507 | 0.70 | — | — | |
| SCHEMBL128005 | 0.69 | TSHR (0.39) | — | |
| SCHEMBL8728825 | 0.69 | — | — | |
| SCHEMBL10347203 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609058-B1 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO CO (JP) | 1998-12-09 | — | — | EP | disclosed |
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |
| EP-0609058-A2 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1994-08-03 | — | — | EP | disclosed |
| EP-0176327-B1 | FUNGICIDAL N-DISUBSTITUTED SULFONAMIDES | CHEVRON RESEARCH COMPANY (US) | 1988-11-23 | — | — | EP | disclosed |
| US-4785019-A | ANTIGROWTH AGENTS | CHEVRON RESEARCH COMPANY (US) | 1988-11-15 | — | — | US | disclosed |
| US-4652556-A | Fungicidal N-cyanoalkyl-N-haloalkylthio sulfonamides | CHEVRON RESEARCH COMPANY (US) | 1987-03-24 | — | — | US | disclosed |
| EP-0176327-A1 | Fungicidal n-disubstituted sulfonamides | CHEVRON RESEARCH COMPANY (US) | 1986-04-02 | — | — | EP | disclosed |