Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8729800 | 1.00 | RARB (0.46) | RARBLMNATP53MAPTLTA4H | |
| SCHEMBL8731567 | 1.00 | RARB (0.46) | RARBLMNATP53MAPTLTA4H | |
| SCHEMBL8729995 | 1.00 | RARB (0.46) | RARBLMNATP53MAPTLTA4H | |
| SCHEMBL8727188 | 1.00 | RARB (0.46) | RARBLMNATP53MAPTLTA4H | |
| SCHEMBL8724529 | 0.82 | RARB (0.41) | RARBLMNATP53MAPTLTA4H | |
| SCHEMBL8724532 | 0.82 | RARB (0.41) | RARBLMNATP53MAPTLTA4H | |
| SCHEMBL9764788 | 0.80 | HRH3 (0.56) | RARBLMNATP53MAPTLTA4H | |
| SCHEMBL9483839 | 0.77 | RARB (0.50) | RARBLMNATP53TSHR | |
| SCHEMBL28063059 | 0.76 | HRH3 (0.57) | LMNATP53MAPTLTA4HNR5A1 | |
| SCHEMBL9155028 | 0.75 | RARB (0.71) | RARBLMNATP53MAPTLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5853613-A | Chiral cyclohexyl compounds | SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1998-12-29 | — | — | US | disclosed |