Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 9/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.40 |
| ▸ | CASP6 | P55212 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | TDO2 | P48775 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL10681217 | 0.77 | HSP90AA1 (0.60) | CA5ACA5BMAPTKDM4EMEN1 | |
| Nitric Acid SCHEMBL11147624 | 0.77 | HSP90AA1 (0.60) | CA5ACA5BMAPTKDM4EMEN1 | |
| Nitric Acid SCHEMBL8397796 | 0.77 | KCNH2 (0.44) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| Dinitrophenylene SCHEMBL27726843 | 0.77 | TSHR (0.65) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL30168529 | 0.76 | — | — | |
| Potassium SCHEMBL30168527 | 0.76 | — | — | |
| SCHEMBL28508440 | 0.76 | — | — | |
| Water SCHEMBL6535893 | 0.76 | — | — | |
| Bicarbonate SCHEMBL1161072 | 0.75 | NAPRT (0.44) | MAPTKDM4EKMT2AALDH1A1TDP1 | |
| Dipyridyl SCHEMBL31707325 | 0.73 | KDM4E (0.64) | MAPTKDM4EALDH1A1TDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789326-A | APPLY TO FIBERS | WEYERHAEUSER COMPANY (US) | 1998-08-04 | — | — | US | disclosed |
| US-5672418-A | FIBERS HAVING HYDROGEN BONDING FUNCTIONAL GROUPS; PARTICLES HAVING FUNCTIONAL GROUPS CAPABLE OF FORMING A HYDROGEN BOND OR A COORDINATE COVALENT BOND; ADHESION | WEYERHAEUSER COMPANY (US) | 1997-09-30 | — | — | US | disclosed |
| US-5641561-A | FIBERS HAVE HYDROGEN BONDING FUNCTIONAL SITES AND BINDERS HAVE VOLATILITY LESS THAN WATER | WEYERHAEUSER COMPANY (US) | 1997-06-24 | — | — | US | disclosed |
| US-5607759-A | Particle binding to fibers | WEYERHAEUSER COMPANY (US) | 1997-03-04 | — | — | US | disclosed |
| US-5547745-A | SUPERABSORBENT POLYMER FIBERS | WEYERHAEUSER COMPANY (US) | 1996-08-20 | — | — | US | disclosed |