Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 15/20 | 0.64 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8758522 | 0.90 | TBXA2R (0.66) | TBXA2RPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8730030 | 0.90 | TBXA2R (0.61) | TBXA2RALOX15TSHRHSD17B10TBXAS1 | |
| SCHEMBL8733707 | 0.89 | TBXA2R (0.53) | TBXA2RTSHR | |
| SCHEMBL10390134 | 0.85 | TBXA2R (0.62) | TBXA2RPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5673556 | 0.82 | TBXA2R (0.85) | TBXA2R | |
| SCHEMBL8731707 | 0.81 | TBXA2R (0.80) | TBXA2R | |
| Water SCHEMBL2762310 | 0.81 | TBXA2R (0.63) | TBXA2RTSHR | |
| SCHEMBL8757930 | 0.80 | TBXA2R (0.82) | TBXA2R | |
| SCHEMBL10357238 | 0.80 | HDAC8 (0.58) | TBXA2RPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10357585 | 0.80 | HDAC8 (0.63) | TBXA2RPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750524-A | ADMINISTERING AN SULFAMIDE SUBSTITUTED INDAN DERIVATIVE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0773019-A1 | HYPERLIPEMIA REMEDY | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-14 | — | — | EP | disclosed |