SCHEMBL8730198

SCHEMBL8730198

CN(C)S(=O)(=O)Cl.CS(=O)(=O)Cl

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
CYP3A4 P08684 1/20 0.36
CA1 P00915 2/20 0.33
GAA P10253 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1112 0.92
Hydrochloric Acid SCHEMBL3518668 0.88
SCHEMBL6612325 0.79 CA1 (0.35) CA1CA2
SCHEMBL1562 0.78
SCHEMBL27337439 0.78 KDM4E (0.56) KDM4ECYP3A4CA1CA2
Hydrochloric Acid SCHEMBL6618237 0.74
Hydrochloric Acid SCHEMBL2125050 0.74
SCHEMBL5316447 0.74
SCHEMBL2723477 0.74 KDM4E (0.50) KDM4ECYP3A4CA1CA2
Ammonia Solution, Strong SCHEMBL4926226 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0865439-A4 COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS ISIS PHARMACEUTICALS INC (US) 1998-11-11 EP disclosed
EP-0865439-A1 COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS ISIS PHARMACEUTICALS, INC. (US) 1998-09-23 EP disclosed
WO-1996040672-A1 COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS ISIS PHARMACEUTICALS, INC. (US) 1996-12-19 WO disclosed