SCHEMBL8730639

SCHEMBL8730639

C=CCCC1CCC(CCC2CCC(c3ccc(COCCC)cc3)CC2)CC1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 3/20 0.39
ESR2 Q92731 8/20 0.38
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
MEN1 O00255 1/20 0.37
MAPK1 P28482 1/20 0.37
KMT2A Q03164 1/20 0.37
SPHK1 Q9NYA1 6/20 0.34
ESR1 P03372 6/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2D6 P10635 1/20 0.31
SPHK2 Q9NRA0 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8730633 1.00 CYP2C9 (0.39) CYP2C9ESR2ALDH1A1LMNAMAPT
SCHEMBL8730627 1.00 CYP2C9 (0.39) CYP2C9ESR2ALDH1A1LMNAMAPT
SCHEMBL8728007 0.99 CYP2C9 (0.39) CYP2C9ESR2ALDH1A1LMNAMAPT
SCHEMBL8728011 0.99 CYP2C9 (0.39) CYP2C9ESR2ALDH1A1LMNAMAPT
SCHEMBL8725096 0.95 CYP2C9 (0.37) CYP2C9ESR2ALDH1A1LMNAMAPT
SCHEMBL8725101 0.95 CYP2C9 (0.37) CYP2C9ESR2ALDH1A1LMNAMAPT
SCHEMBL8730596 0.93 CYP2C9 (0.37) CYP2C9ESR2ALDH1A1LMNAMAPT
SCHEMBL8730600 0.93 CYP2C9 (0.37) CYP2C9ESR2ALDH1A1LMNAMAPT
SCHEMBL8730590 0.93 CYP2C9 (0.37) CYP2C9ESR2ALDH1A1LMNAMAPT
SCHEMBL8731480 0.93 SPHK1 (0.39) CYP2C9ESR2ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0882695-A1 BENZYL ETHER DERIVATIVES, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY CHISSO CORPORATION (JP) 1998-12-09 EP disclosed