Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.71 |
| ▸ | CA2 | P00918 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | LDHA | P00338 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.31 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL62560 | 1.00 | — | — | |
| Bicarbonate SCHEMBL2454267 | 1.00 | — | — | |
| Bicarbonate SCHEMBL5918699 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL873151 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL5918698 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL5961367 | 1.00 | — | — | |
| Bicarbonate SCHEMBL120118 | 1.00 | — | — | |
| Bicarbonate SCHEMBL943607 | 1.00 | — | — | |
| Bicarbonate SCHEMBL5961366 | 1.00 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL2505771 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 416 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122036344-A | Ceramic material for capacitor and preparation method thereof | 东莞市健而威电子科技有限公司 | 2026-05-15 | — | — | CN | claimed |
| US-12420534-B2 | Aerogel polysiloxane layer laminate structure | DOW SILICONES CORPORATION (US) | 2025-09-23 | — | — | US | claimed |
| US-12325648-B2 | Recirculating water system composition | BIO-LAB, INC. (US) | 2025-06-10 | — | — | US | claimed |
| WO-2025096219-A1 | CURABLE SILICONE COMPOSITION AND USES THEREOF | ROGERS CORPORATION (US) | 2025-05-08 | — | — | WO | claimed |
| WO-2025006103-A1 | COMPRESSIBLE SILICONE FOAM AND METHOD FOR THE MANUFACTURE THEREOF | ROGERS CORPORATION (US) | 2025-01-02 | — | — | WO | claimed |
| US-20240425660-A1 | COMPRESSIBLE SILICONE FOAM AND METHOD FOR THE MANUFACTURE THEREOF | ROGERS CORP (US) | 2024-12-26 | — | — | US | claimed |
| US-12119467-B2 | Composite thermal management sheet, method of manufacture, and articles using the same | ROGERS CORPORATION (US) | 2024-10-15 | — | — | US | claimed |
| EP-4347248-A1 | MULTILAYER COMPOSITE WITH THERMAL BARRIER PROPERTIES | Saint-Gobain Performance Plastics Corporation (US) | 2024-04-10 | — | — | EP | claimed |
| EP-4347695-A1 | FOAM LAYER WITH THERMAL BARRIER PROPERTIES | Saint-Gobain Performance Plastics Corporation (US) | 2024-04-10 | — | — | EP | claimed |
| US-20240088483-A1 | THERMALLY INSULATING MULTILAYER SHEET, METHOD OF MANUFACTURE, AND ARTICLES USING THE SAME | ROGERS CORP (US) | 2024-03-14 | — | — | US | claimed |
| US-6369000-B1 | IMPREGNATING ALUMINA WITH A MELTED METAL COMPOUND, CALCINING, DOES NOT INVOLVE PHYSICAL MIXING OR COPRECIPITATION | PHILLIPS PETROLEUM COMPANY | 2002-04-09 | — | — | US | claimed |
| WO-2002020406-A1 | IMPURITY REMOVAL | AUSTRALIAN MAGNESIUM OPERATIONS PTY LTD (AU) | 2002-03-14 | — | — | WO | claimed |
| WO-2002011760-A1 | PARENTERAL VACCINE FORMULATIONS AND USES THEREOF | Alk-Abelló A/S (DK) | 2002-02-14 | — | — | WO | claimed |
| US-20010046943-A1 | HYDROCARBON HYDROGENATION CATALYST AND PROCESS | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2001-11-29 | — | — | US | claimed |
| WO-2001019763-A1 | CATALYST COMPOSITION AND PROCESS FOR MAKING THE COMPOSITION | PHILLIPS PETROLEUM COMPANY (US) | 2001-03-22 | — | — | WO | claimed |
| WO-2001019514-A1 | PROCESS FOR PRODUCING A METAL ALUMINATE CATALYST SUPPORT | PHILIPS PETROLEUM COMPANY (US) | 2001-03-22 | — | — | WO | claimed |
| US-5627303-A | ALDOL CONDENSATION OF ACETONE, CALCINED MAGNESIUM/ALUMINUM MIXED OXIDE CATALYST | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-05-06 | — | — | US | claimed |
| EP-0640387-A1 | Preparation of isophorone using a magnesium/aluminum mixed oxide catalyst | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1995-03-01 | — | — | EP | claimed |
| EP-0640388-A1 | Magnesium/aluminum mixed oxide catalysts and their use in the production of aminoethers | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1995-03-01 | — | — | EP | claimed |
| US-5220875-A | Reacting sulfur dioxide with calcined sorbent in presence of oxygen to form solid inorganic sulfate | AMERICAN OXYCARB CORPORATION (US) | 1993-06-22 | — | — | US | claimed |