Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 14/20 | 0.48 |
| ▸ | HTR7 | P34969 | 4/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | CTRC | Q99895 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358686 | 0.92 | F2 (0.57) | F2 | |
| SCHEMBL8726622 | 0.92 | F2 (0.57) | F2PRSS2CTRC | |
| SCHEMBL8726814 | 0.90 | F2 (0.48) | F2PRSS2CTRC | |
| SCHEMBL8727415 | 0.89 | F2 (0.48) | F2HTR7ADRA1DHTR2CADRA1A | |
| SCHEMBL8729919 | 0.85 | F2 (0.43) | F2PRSS2CTRC | |
| SCHEMBL8732116 | 0.84 | F2 (0.39) | F2PRSS2CTRC | |
| SCHEMBL8733780 | 0.84 | F2 (0.39) | F2PRSS2CTRC | |
| SCHEMBL7372831 | 0.84 | F2 (0.54) | F2HTR7ADRA1DHTR2CADRA1A | |
| SCHEMBL8726747 | 0.83 | F2 (0.41) | F2PRSS2CTRC | |
| SCHEMBL8728985 | 0.83 | F2 (0.68) | F2PRSS2CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778839-B1 | NOVEL PHOSPHANE OXIDES, METHOD OF PREPARING THEM AND DRUGS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-23 | — | — | EP | disclosed |