Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8732183 | 1.00 | HTR2A (0.36) | HTR2AHTR2CHTR2BSIGMAR1SPHK1 | |
| SCHEMBL8732177 | 1.00 | HTR2A (0.36) | HTR2AHTR2CHTR2BSIGMAR1SPHK1 | |
| SCHEMBL8732178 | 1.00 | HTR2A (0.36) | HTR2AHTR2CHTR2BSIGMAR1SPHK1 | |
| SCHEMBL8728021 | 0.91 | SPHK1 (0.35) | HTR2AHTR2CHTR2BSIGMAR1SPHK1 | |
| SCHEMBL8728016 | 0.91 | SPHK1 (0.35) | HTR2AHTR2CHTR2BSIGMAR1SPHK1 | |
| SCHEMBL8728012 | 0.91 | SPHK1 (0.35) | HTR2AHTR2CHTR2BSIGMAR1SPHK1 | |
| SCHEMBL8728024 | 0.91 | SPHK1 (0.35) | HTR2AHTR2CHTR2BSIGMAR1SPHK1 | |
| SCHEMBL8730397 | 0.89 | SPHK1 (0.38) | HTR2AHTR2CHTR2BSIGMAR1SPHK1 | |
| SCHEMBL8730401 | 0.89 | SPHK1 (0.38) | HTR2AHTR2CHTR2BSIGMAR1SPHK1 | |
| SCHEMBL8730388 | 0.89 | SPHK1 (0.38) | HTR2AHTR2CHTR2BSIGMAR1SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882695-A1 | BENZYL ETHER DERIVATIVES, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY | CHISSO CORPORATION (JP) | 1998-12-09 | — | — | EP | disclosed |