⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27921412 | 1.00 | — | — | |
| SCHEMBL6691343 | 1.00 | — | — | |
| SCHEMBL8423052 | 0.72 | — | — | |
| SCHEMBL95392 | 0.70 | — | — | |
| SCHEMBL3198345 | 0.70 | — | — | |
| SCHEMBL11597297 | 0.70 | — | — | |
| Isopropyl Alcohol SCHEMBL28388486 | 0.70 | — | — | |
| Isopropyl Alcohol SCHEMBL10902290 | 0.70 | — | — | |
| Isopropyl Alcohol SCHEMBL14797686 | 0.68 | — | — | |
| SCHEMBL2547986 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2625217-B1 | CHAIN-EXTENDED POLYSILOXANE CROSSLINKERS WITH DANGLING HYDROPHILIC POLYMER CHAINS | NOVARTIS AG (CH) | 2018-07-04 | — | — | EP | claimed |
| CN-105106199-A | Methods of using MEK inhibitors | EXELIXIS INC | 2015-12-02 | — | — | CN | claimed |
| US-8835525-B2 | Chain-extended polysiloxane crosslinkers with dangling hydrophilic polymer chains | NOVARTIS AG (CH) | 2014-09-16 | — | — | US | claimed |
| EP-2625217-A1 | CHAIN-EXTENDED POLYSILOXANE CROSSLINKERS WITH DANGLING HYDROPHILIC POLYMER CHAINS | Novartis AG (CH) | 2013-08-14 | — | — | EP | claimed |
| CN-103180319-A | Inhibitors of semicarabazide - sensitive amine oxidase | PROXIMAGEN LTD | 2013-06-26 | — | — | CN | claimed |
| US-20130045872-A1 | METHODS OF TARGETED SEQUENCING | CENTRILLION TECHNOLOGY HOLDINGS CORPORATION (KY) | 2013-02-21 | — | — | US | claimed |
| CN-102858995-A | Methods of targeted sequencing | CENTRILLION TECHNOLOGY HOLDING CORP | 2013-01-02 | — | — | CN | claimed |
| WO-2012047964-A1 | CHAIN-EXTENDED POLYSILOXANE CROSSLINKERS WITH DANGLING HYDROPHILIC POLYMER CHAINS | NOVARTIS AG (CH) | 2012-04-12 | — | — | WO | claimed |
| WO-2011032040-A1 | METHODS OF TARGETED SEQUENCING | CENTRILLION TECHNOLOGY HOLDING CORPORATION (KY) | 2011-03-17 | — | — | WO | claimed |
| CN-1061409-A | New compound, contain drug regimen of these new compounds and preparation method thereof | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1992-05-27 | — | — | CN | claimed |
| CN-116751169-A | N- (2-oxo propyl) acetamide derivative and preparation method and application thereof | 重庆市畜牧科学院 | 2023-09-15 | — | — | CN | disclosed |
| US-11578074-B2 | Nitrogenous heterocyclic compound, preparation method, intermediate, composition, and application | Shanghai Pharmaceuticals Holding Cd., Ltd. (CN) | 2023-02-14 | — | — | US | disclosed |
| CN-114088855-B | Feces biomarker for early diagnosis of tibial cartilage dysplasia of broiler chicken and application thereof | 河南农业大学 | 2022-10-28 | — | — | CN | disclosed |
| CN-115028617-A | Heterocyclic inhibitors of CBP/EP300 and their use in the treatment of cancer | 基因泰克公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-106714844-B | Anthracycline disulfide intermediates, antibody-drug conjugates and methods | 基因泰克公司 | 2022-08-05 | — | — | CN | disclosed |
| US-4719288-A | HYPOTENSIVE | CIBA-GEIGY CORPORATION (US) | 1988-01-12 | — | — | US | disclosed |
| US-4613676-A | PEPTIDES | CIBA-GEIGY CORPORATION (US) | 1986-09-23 | — | — | US | disclosed |
| EP-0143746-A2 | 5-Amino 4-hydroxy-valeryl-substituted derivatives | CIBA-GEIGY AG (CH) | 1985-06-05 | — | — | EP | disclosed |
| US-4308269-A | ANTITUMOUR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-12-29 | — | — | US | disclosed |
| US-4264766-A | Immunological diagnostic reagents | HOFFMANN-LA ROCHE INC. (US) | 1981-04-28 | — | — | US | disclosed |